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Letters in Drug Design & Discovery


ISSN (Print): 1570-1808
ISSN (Online): 1875-628X

Accumulation Effects of 3-N-Benzyloxycarbonyl-β-aminobutyric Salicylate on the Alkaloids in Catharanthus roseus Cells

Author(s): Er-Bing Yang, Yong Wang, Hong-Jun Zang, Zheng-Ming Li and Xing-Hai Liu

Volume 13, Issue 2, 2016

Page: [117 - 120] Pages: 4

DOI: 10.2174/1570180812666150723001034

Price: $65


Plant growth regulators with the suitable concentrations had obvious effects on the accumulation of indole alkaloids in Catharanthusroseus cells.Four new compounds were synthesized as plant growth regulators and the accumulation effects of indole alkaloids in Catharanthusroseus cells were determined. Furthermore, some of them had the ability of promoting the accumulation of catharanthineandajmalicine in Catharanthusroseus cells. Compound 2 and 4 exhibited the best effects on the indole alkaloids production at 1μg mL-1; compound 2 displayed promoted the accumulation of catharanthineat 1μg mL-1, even at 10μg mL-1.

Keywords: Accumulation, salicylate, catharanthus roseus cells, catharanthine, ajmalicine.

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