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Mini-Reviews in Medicinal Chemistry


ISSN (Print): 1389-5575
ISSN (Online): 1875-5607

A System Review of Anti-fibrogenesis Effects of Compounds Derived from Chinese Herbal Medicine

Author(s): Yanling Zhao, Xiao Ma, Jiabo Wang, Xuan He, Yaming Zhang, Ye Wang, Honghong Liu, Honghui Shen and Xiaohe Xiao

Volume 16, Issue 2, 2016

Page: [163 - 175] Pages: 13

DOI: 10.2174/1389557515666150709121908

Price: $65


Chinese herbal medicine (CHM), an alternative and complementary medicine, has been applied in various diseases. Recently, a number of anti-liver fibrogenesis compounds exhibiting antiliver fibrosis effects have been discovered in CHM. In this review, we reviewed the published data on their anti-fibrosis effects and discussed the possible underlying mechanisms. More investigations are needed to improve the insight into therapeutic effect of CHM on liver fibrosis.

Keywords: Chinese herbal medicine, Extracellular matrix, Hepatic stellate cell, Liver fibrosis.

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