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Current Topics in Medicinal Chemistry


ISSN (Print): 1568-0266
ISSN (Online): 1873-4294

Progress in Self-assembling Peptide-based Nanomaterials for Biomedical Applications

Author(s): Cui-Yun Yu, Wen Huang, Zhi-Ping Li, Xiao-Yong Lei, Dong-Xiu He and Lichun Sun

Volume 16, Issue 3, 2016

Page: [281 - 290] Pages: 10

DOI: 10.2174/1568026615666150701114527

Price: $65


Self-assembled peptide nanomaterials display the advantageous properties of injectability, biodegradability and biocompatibility. These peptide nanomaterials, by self-assembling, can be widely applied in such fields as drug delivery (small molecules and large molecules), regenerative medicine and nanobiotechnology. In this review, we mainly discuss the properties of these peptide nanomaterials in their physical, chemical and biological aspects. Also discussed are recent advances in their potential applications as drug delivery systems and for uses in regenerative medicine. These current advances show a bright future for the development and clinical applications of self-assembled peptide-based nanotechnology and nanomedicine. However, there are still some big challenges for us to face before these peptide nanomaterials eventually can be used for the treatment of human diseases.

Keywords: Nanomaterials, Peptide, Regenerative medicine, Self-assembly, Targeted delivery system.

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