Abstract
Symptomatic distresses associated with common ophthalmic infections and their persistence, have remained a tribulation with repeated occurrences. Although being a directly accessible organ, traditional therapeutic strategies exhibiting seemingly fruitful outcome in treatment and prognosis of eye disorders call for improvement in disease intervention. This is due to frequent challenges presented by the ophthalmic environment. Contemporary research has addressed these challenges by applying nanotechnology as a central concept in designing more proficient diagnostic and therapeutic systems for eye ailments. Within such nanosystems (dendrimers, aptamers, metal nanoparticles, etc.), bioactive agents, drugs and genetic materials can be entrapped and these form the key elements that act at the biomolecular stage and bestow a high level of efficacy towards eradication of disease causatives and specificity for recognition and capture aiding diagnostic processes. In the current review, we present researched and patented nanocentric technologies as promising tools in detection and treatment of ophthalmic ailments.
Keywords: Diagnosis, drug delivery, nanosystems, nanotherapeutic modules, ophthalmics.
Current Pharmaceutical Design
Title:Multidimensional Ophthalmic Nanosystems for Molecular Detection and Therapy of Eye Disorders
Volume: 21 Issue: 22
Author(s): Swati Vyas, Pratik Kakade, Manasi Chogale, John Disouza and Vandana Patravale
Affiliation:
Keywords: Diagnosis, drug delivery, nanosystems, nanotherapeutic modules, ophthalmics.
Abstract: Symptomatic distresses associated with common ophthalmic infections and their persistence, have remained a tribulation with repeated occurrences. Although being a directly accessible organ, traditional therapeutic strategies exhibiting seemingly fruitful outcome in treatment and prognosis of eye disorders call for improvement in disease intervention. This is due to frequent challenges presented by the ophthalmic environment. Contemporary research has addressed these challenges by applying nanotechnology as a central concept in designing more proficient diagnostic and therapeutic systems for eye ailments. Within such nanosystems (dendrimers, aptamers, metal nanoparticles, etc.), bioactive agents, drugs and genetic materials can be entrapped and these form the key elements that act at the biomolecular stage and bestow a high level of efficacy towards eradication of disease causatives and specificity for recognition and capture aiding diagnostic processes. In the current review, we present researched and patented nanocentric technologies as promising tools in detection and treatment of ophthalmic ailments.
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Cite this article as:
Vyas Swati, Kakade Pratik, Chogale Manasi, Disouza John and Patravale Vandana, Multidimensional Ophthalmic Nanosystems for Molecular Detection and Therapy of Eye Disorders, Current Pharmaceutical Design 2015; 21 (22) . https://dx.doi.org/10.2174/1381612821666150531171052
DOI https://dx.doi.org/10.2174/1381612821666150531171052 |
Print ISSN 1381-6128 |
Publisher Name Bentham Science Publisher |
Online ISSN 1873-4286 |
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