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Recent Patents and Topics on Imaging (Discontinued)


ISSN (Print): 2451-8271
ISSN (Online): 2451-8255

An Overview of Labeled Porphyrin Molecules in Medical Imaging

Author(s): Nasim Vahidfar and Amir R. Jalilian

Volume 5, Issue 1, 2015

Page: [3 - 12] Pages: 10

DOI: 10.2174/2451827105666150522235440

Price: $65


Porphyrins are approved as agents to localize malignant tissues by several investigators. There is a great potential interest in the use of porphyrin derivatives capable of high selective accumulation in malignant tissues for the imaging of malignancies. Whilst the porphyrin-based compounds penetrate tumor cells selectively and remain constantly, numerous analogues of porphyrins with different peripheral functional groups have been labeled with various metals and radiometals for imaging purposes, including magnetic resonance imaging (MRI) and nuclear imaging techniques (SPECT/PET). This review summarizes recent advances in the preparation of labeled porphyrins for imaging purposes.

Keywords: Functional, imaging, malignancies, MRI, PET, porphyrin, SPECT.

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