Molecular Targets of Omega-3 Fatty Acids for Cancer Therapy

Title:Molecular Targets of Omega-3 Fatty Acids for Cancer Therapy

Volume: 15 Issue: 7

Author(s): K. Pandima Devi, T. Rajavel, G. L. Russo, M. Daglia, S. F. Nabavi and S. M. Nabavi

Affiliation:

• Applied Biotechnology Research Center, Baqiyatallah University of Medical Sciences, Tehran, P.O. Box 19395-5487, Iran.,Iran

Keywords: Anticancer, fish oil, molecular targets, omega-3 polyunsaturated fatty acids.

Abstract: Nowadays, dietary guidelines acknowledge the therapeutic role of omega-3 polyunsaturated fatty acids, as the most important class of fatty acids, against different human diseases. During the last two decades, the average level of consumption of omega-3 polyunsaturated fatty acids has increased from 0.1 to 0.2 g per day. Omega-3 polyunsaturated fatty acids are a group of long-chain polyunsaturated fatty acids which are identified in different foods such as fatty fish, shellfish, and vegetable oils. A growing body of epidemiological and experimental evidence supports the anticancer effects of omega-3 polyunsaturated fatty acids, which led to the identification of their molecular targets in several cancer models. The present review focuses on the basic evidence supporting the potential applications of omega-3 polyunsaturated fatty acids in cancer therapy.

Cite this article as:

Devi Pandima K., Rajavel T., Russo L. G., Daglia M., Nabavi F. S. and Nabavi M. S., Molecular Targets of Omega-3 Fatty Acids for Cancer Therapy, Anti-Cancer Agents in Medicinal Chemistry 2015; 15(7) . https://dx.doi.org/10.2174/1871520615666150424124606