Abstract
Along with the exuberant development of nanotechnology, a large number of nanoformulations or non materials are successfully applied in the clinics, biomedicine, cosmetics and industry. Despite some unique advantages of nanoformulations, there exist potentially worrying toxic effects, particularly those related to metal and metal-containing nanoparticles (NPs). Although various researches have been conducted to assess the metallic and metal-containing nanoparticles toxic effects, only little is known about the toxicity expressive types and evaluation, reasons and mechanisms, influencing factors and research methods of metal and metal-containing nanotoxicity. Therefore, it is of importance to acquire a better understanding of metal and metal-containing nanoparticles toxicity for medical application. This review presents a summary on the metal and metal-containing nanoparticles toxicity research progress consulting relevant literature.
Keywords: Influencing factors, metal and metal-containing nanoparticles, reason and mechanism, research methods, toxicity expressive types, toxicity research progress.
Mini-Reviews in Medicinal Chemistry
Title:Nanotoxicity: The Toxicity Research Progress of Metal and Metal- Containing Nanoparticles
Volume: 15 Issue: 7
Author(s): Lingling Ding, Zhidong Liu, Mike Okweesi Aggrey, Chunhua Li, Jing Chen and Ling Tong
Affiliation:
Keywords: Influencing factors, metal and metal-containing nanoparticles, reason and mechanism, research methods, toxicity expressive types, toxicity research progress.
Abstract: Along with the exuberant development of nanotechnology, a large number of nanoformulations or non materials are successfully applied in the clinics, biomedicine, cosmetics and industry. Despite some unique advantages of nanoformulations, there exist potentially worrying toxic effects, particularly those related to metal and metal-containing nanoparticles (NPs). Although various researches have been conducted to assess the metallic and metal-containing nanoparticles toxic effects, only little is known about the toxicity expressive types and evaluation, reasons and mechanisms, influencing factors and research methods of metal and metal-containing nanotoxicity. Therefore, it is of importance to acquire a better understanding of metal and metal-containing nanoparticles toxicity for medical application. This review presents a summary on the metal and metal-containing nanoparticles toxicity research progress consulting relevant literature.
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Cite this article as:
Ding Lingling, Liu Zhidong, Okweesi Aggrey Mike, Li Chunhua, Chen Jing and Tong Ling, Nanotoxicity: The Toxicity Research Progress of Metal and Metal- Containing Nanoparticles, Mini-Reviews in Medicinal Chemistry 2015; 15 (7) . https://dx.doi.org/10.2174/138955751507150424104334
DOI https://dx.doi.org/10.2174/138955751507150424104334 |
Print ISSN 1389-5575 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5607 |
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