Abstract
Pyridinium chlorochromate (PCC) is an important reagent in organic synthesis used primarily for the selective oxidation of alcohols to give carbonyl compounds. Although a variety of related compounds are known with similar reactivity, PCC offers exclusively the advantage of the selective oxidation of alcohols to aldehydes, whereas many other reagents were less selective. Disadvantages of using PCC are the tedious reaction workup and its toxicity, very well compensated by selective oxidation, observed using this reagent as an oxidant. This useful oxidant was first synthesized and used by E. J. Corey and J. William Suggs in 1972.
Keywords: Pyridinium chlorochromate (PCC), organic synthesis, alcohol, oxidation, carbonyl compounds, selective oxidation.
Graphical Abstract
Call for Papers in Thematic Issues
Exploring the Role of Chemical Graph Theory in Advancing Current Organic Synthesis
Organic synthesis is a fundamental discipline in chemistry, crucial for the creation of complex molecules with diverse applications in pharmaceuticals, materials science, and beyond. However, the process of designing efficient synthetic routes for target molecules remains challenging. Chemical graph theory, a branch of theoretical chemistry, offers powerful tools for understanding ...read more
Photoswitches for Molecular Recognition
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