Abstract
Recent developments in the chemistry of η3-allylruthenium complexes (synthesis and reactivity) are described. Among different possible preparations, their straightforward formation via oxidative addition of allylic substrates occurs either at ruthenium(0) or ruthenium(II) centres. Subsequent reaction with an electrophile or a nucleophile is the basis of their ambiphilic involvement in catalysis. In this review, we focus on catalytic substitution of allylic substrates by C, N, O and S-nucleophiles, and show that selected ligands make possible stereospecific, as well as regio- and enantioselective substitutions.
Keywords: diallylation, Phosphorus ligands, triphenylphosphine, halide coordination, isomerism
Current Organic Chemistry
Title: η3-Allylruthenium Complexes and Ruthenium-Catalysed Nucleophilic Substitution of Allylic Substrates
Volume: 10 Issue: 2
Author(s): Bernard Demerseman, Mbaye D. Mbaye, Christian Bruneau and Jean-Luc Renaud
Affiliation:
Keywords: diallylation, Phosphorus ligands, triphenylphosphine, halide coordination, isomerism
Abstract: Recent developments in the chemistry of η3-allylruthenium complexes (synthesis and reactivity) are described. Among different possible preparations, their straightforward formation via oxidative addition of allylic substrates occurs either at ruthenium(0) or ruthenium(II) centres. Subsequent reaction with an electrophile or a nucleophile is the basis of their ambiphilic involvement in catalysis. In this review, we focus on catalytic substitution of allylic substrates by C, N, O and S-nucleophiles, and show that selected ligands make possible stereospecific, as well as regio- and enantioselective substitutions.
Export Options
About this article
Cite this article as:
Demerseman Bernard, Mbaye D. Mbaye, Bruneau Christian and Renaud Jean-Luc, η3-Allylruthenium Complexes and Ruthenium-Catalysed Nucleophilic Substitution of Allylic Substrates, Current Organic Chemistry 2006; 10 (2) . https://dx.doi.org/10.2174/138527206775192979
DOI https://dx.doi.org/10.2174/138527206775192979 |
Print ISSN 1385-2728 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5348 |
Call for Papers in Thematic Issues
Catalytic C-H bond activation as a tool for functionalization of heterocycles
The major topic is the functionalization of heterocycles through catalyzed C-H bond activation. The strategies based on C-H activation not only provide straightforward formation of C-C or C-X bonds but, more importantly, allow for the avoidance of pre-functionalization of one or two of the cross-coupling partners. The beneficial impact of ...read more
Electrochemical C-X bond formation
Conventional methods for carrying out carbon–X bond formation are typically conducted at harsh reaction conditions, and rely on expensive catalysts as well as the use of stoichiometric, and perhaps toxic, oxidants. In this regard, electrochemical synthesis has recently been recognized as a sustainable and scalable strategy for the construction of ...read more
From Lab Bench to Algorithm: The Future of Organic Chemistry Powered by AI
Organic chemistry, with its intricate dance of molecules and reactions, is undergoing a transformation fuelled by the power of Artificial Intelligence (AI) and Machine Learning (ML). The integration of AI/ML with Organic Chemistry is revolutionizing the field by enhancing the efficiency and accuracy of chemical research and development. These technologies ...read more
N-Heterocyclics: Synthesis, Computational Studies, and Coordination Chemistry - A synthetic perspective
N-heterocycles, such as phenanthroline, quinoline, or their organometallic complexes, are widely used in a variety of fields, including chemistry, biochemistry, and coordination chemistry. They play a key role in many chemical and biological processes as biological ligands, medicinal agents, catalysts in organic synthesis, molecular probes and sensors, as well as ...read more
Related Journals
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
- Announcements
Related Articles
-
Food Addiction and Neuroimaging
Current Pharmaceutical Design Small Molecule Immunosuppressive Agents in Experimental and Clinical Transplantation
Current Drug Targets - Cardiovascular & Hematological Disorders LIST OF REVIEWERS (ACKNOWLEDGEMENTS)
Recent Patents on Inflammation & Allergy Drug Discovery Phenolic Compounds in Prevention and Treatment of Skin Cancers: A Review
Current Medicinal Chemistry Predicting Enhancers from Multiple Cell Lines and Tissues across Different Developmental Stages Based On SVM Method
Current Bioinformatics Triamcinolone Acetonide Inhibits p38MAPK Activation and Neuronal Apoptosis in Early Diabetic Retinopathy
Current Molecular Medicine The Role of Transcriptome Analysis in Pre-Clinical Toxicology
Current Molecular Medicine Metabolism of the Endocannabinoids Anandamide and 2-Arachidonoyl Glycerol, A Review, with Emphasis on the Pharmacology of Fatty Acid Amide Hydrolase, A Possible Target for the Treatment of Neurodegenerative Diseases and Pain
Current Medicinal Chemistry - Central Nervous System Agents Ceramide in Chemotherapy of Tumors
Recent Patents on Anti-Cancer Drug Discovery Inhaled Corticosteroids In Treatment of Cystic Fibrosis
Anti-Inflammatory & Anti-Allergy Agents in Medicinal Chemistry A Systematic Review of Randomized Controlled Trials Examining the Nephroprotective Properties of Antihypertensive Medications
Current Hypertension Reviews Anti-Inflammatory Effects of Physical Activity in Relationship to Improved Cognitive Status in Humans and Mouse Models of Alzheimers Disease
Current Alzheimer Research Occurrence and Biological Activities of Phenylpropionyl Iridoids
Mini-Reviews in Medicinal Chemistry Recent Advances in the Synthesis of Unnatural α-Amino Acids - An Updated Version
Current Organic Chemistry Dubious Results of Remdisivir Ultimately in Solidarity; Diversity of Severity of Illness is Doubtful
New Emirates Medical Journal Editorial from Guest Editor [Hot Topic:Animal Venoms: From Deadly Arsenals (Toxins) to Therapeutic Drug Candidates (Guest Editor: Jean-Marc Sabatier)]
Inflammation & Allergy - Drug Targets (Discontinued) Taking Advantage of Plant Defense Mechanisms to Promote Human Health. Exploitation of Plant Natural Products for Preventing or Treating Human Disease: Second of Two Parts
Endocrine, Metabolic & Immune Disorders - Drug Targets Epithelial Mesenchymal Transition in Cancer Progression: Prev entive Phytochemicals
Recent Patents on Anti-Cancer Drug Discovery Targeting the MCP-1/CCR2 System in Diabetic Kidney Disease
Current Vascular Pharmacology Understanding Respiratory Syncytial Virus Infection to Improve Treatment and Immunity
Current Molecular Medicine