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Mini-Reviews in Medicinal Chemistry


ISSN (Print): 1389-5575
ISSN (Online): 1875-5607

An Overview of the Pharmacological Properties and Potential Applications of Natural Monoterpenes

Author(s): Agata Koziol, Agnieszka Stryjewska, Tadeusz Librowski, Kinga Salat, Magdalena Gawel, Andrzej Moniczewski and Stanisław Lochynski

Volume 14, Issue 14, 2014

Page: [1156 - 1168] Pages: 13

DOI: 10.2174/1389557514666141127145820

Price: $65


Monoterpenes, the major components of essential oils, belong to the group of isoprenoids containing ten carbon atoms. Being widely distributed in the plant kingdom they are extensively used in cuisine and human health care products. Studies have shown that both natural monoterpenes and their synthetic derivatives are endowed with various pharmacological properties including antifungal, antibacterial, antioxidant, anticancer, antiarrhythmic, anti-aggregating, local anesthetic, antinociceptive, anti-inflammatory, antihistaminic and anti-spasmodic activities. Monoterpenes act also as regulators of growth, heat, transpiration, tumor inhibitors, inhibitors of oxidative phosphorylation, insect repellants, feline and canine attractants and antidiabetics. These interesting activities which might be potentially used not only in pharmaceutical, but also food and cosmetic industries are discussed below.

Keywords: Acyclic, antibacterial, anticancer, antifungal, anti-inflammatory, antioxidant, antiviral, essential oils, hypotensive and vasorelaxant, local anesthetic, monocyclic and bicyclic monoterpenes, monoterpene activity, stereochemistry.

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