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Current Respiratory Medicine Reviews


ISSN (Print): 1573-398X
ISSN (Online): 1875-6387

Review Article

Markers of Systemic Inflammation in Obstructive Sleep Apnea Syndrome

Author(s): Kostas Archontogeorgis, Evangelia Nena, Maria Xanthoudaki and Demosthenes Bouros

Volume 12, Issue 2, 2016

Page: [142 - 151] Pages: 10

DOI: 10.2174/1573398X10666141105234647

Price: $65


Obstructive sleep apnea syndrome (OSAS) is a common disorder characterized by recurrent episodes of upper airway obstruction resulting in oxygen desaturations and sleep disruption. OSAS is associated with an augmented risk for cardiovascular and cerebrovascular morbidity and mortality. Several mechanisms have been proposed to explain the association between OSAS and cardiovascular dysfunction. Low-grade systemic inflammation may contribute to the development of the cardiovascular and metabolic diseases associated with OSAS. The purpose of this review is to summarize current evidence on the association between OSAS and markers of systemic inflammation.

Keywords: Inflammation, inflammatory markers, obstructive sleep apnea syndrome.

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