Abstract
Among the family of nitrogen-containing heterocycles, quinoxalinone (or quinoxalin-2-one) core, characterized by pyrazin-2(1H)-one fused to benzene ring at two adjacent carbon atoms, has been frequently found in a variety of pharmacologically active compounds with biological or pharmaceutical applications. In this article, we highlighted the synthetic methods of this scaffold, as well as its derivates.
Keywords: Quinoxalinone, reaction mechanism, synthetic method.
Mini-Reviews in Organic Chemistry
Title:Advances in the Chemistry of Quinoxalinone Derivatives
Volume: 12 Issue: 1
Author(s): Leilei Shi, Hua Zhou, Jifeng Wu and Xun Li
Affiliation:
Keywords: Quinoxalinone, reaction mechanism, synthetic method.
Abstract: Among the family of nitrogen-containing heterocycles, quinoxalinone (or quinoxalin-2-one) core, characterized by pyrazin-2(1H)-one fused to benzene ring at two adjacent carbon atoms, has been frequently found in a variety of pharmacologically active compounds with biological or pharmaceutical applications. In this article, we highlighted the synthetic methods of this scaffold, as well as its derivates.
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Cite this article as:
Shi Leilei, Zhou Hua, Wu Jifeng and Li Xun, Advances in the Chemistry of Quinoxalinone Derivatives, Mini-Reviews in Organic Chemistry 2015; 12 (1) . https://dx.doi.org/10.2174/1570193X11666141029004418
DOI https://dx.doi.org/10.2174/1570193X11666141029004418 |
Print ISSN 1570-193X |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-6298 |
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