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Mini-Reviews in Organic Chemistry

Editor-in-Chief

ISSN (Print): 1570-193X
ISSN (Online): 1875-6298

Advances in the Chemistry of Quinoxalinone Derivatives

Author(s): Leilei Shi, Hua Zhou, Jifeng Wu and Xun Li

Volume 12, Issue 1, 2015

Page: [96 - 112] Pages: 17

DOI: 10.2174/1570193X11666141029004418

Price: $65

Abstract

Among the family of nitrogen-containing heterocycles, quinoxalinone (or quinoxalin-2-one) core, characterized by pyrazin-2(1H)-one fused to benzene ring at two adjacent carbon atoms, has been frequently found in a variety of pharmacologically active compounds with biological or pharmaceutical applications. In this article, we highlighted the synthetic methods of this scaffold, as well as its derivates.

Keywords: Quinoxalinone, reaction mechanism, synthetic method.

Graphical Abstract

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