Abstract
Progress in cancer treatment remains challenging because of the great nature of tumor cells to be drug resistant. However, advances in the field of nanotechnology have enabled the delivery of drugs for cancer treatment by passively and actively targeting to tumor cells with nanoparticles. Dramatic improvements in nanotherapeutics, as applied to cancer, have rapidly accelerated clinical investigations. In this review, drug-targeting systems using nanotechnology and approved and clinically investigated nanoparticles for cancer therapy are discussed. In addition, the rationale for a nanotechnological approach to cancer therapy is emphasized because of its promising advances in the treatment of cancer patients.
Keywords: Cancer, drug delivery, drug, nanoparticles, nanotechnology, polimeric, targeting, therapeutics.
Mini-Reviews in Medicinal Chemistry
Title:Drug Targeting Systems for Cancer Therapy: Nanotechnological Approach
Volume: 14 Issue: 13
Author(s): R. Seda Tigli Aydin
Affiliation:
Keywords: Cancer, drug delivery, drug, nanoparticles, nanotechnology, polimeric, targeting, therapeutics.
Abstract: Progress in cancer treatment remains challenging because of the great nature of tumor cells to be drug resistant. However, advances in the field of nanotechnology have enabled the delivery of drugs for cancer treatment by passively and actively targeting to tumor cells with nanoparticles. Dramatic improvements in nanotherapeutics, as applied to cancer, have rapidly accelerated clinical investigations. In this review, drug-targeting systems using nanotechnology and approved and clinically investigated nanoparticles for cancer therapy are discussed. In addition, the rationale for a nanotechnological approach to cancer therapy is emphasized because of its promising advances in the treatment of cancer patients.
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Tigli Aydin Seda R., Drug Targeting Systems for Cancer Therapy: Nanotechnological Approach, Mini-Reviews in Medicinal Chemistry 2014; 14 (13) . https://dx.doi.org/10.2174/1389557514666140820115052
DOI https://dx.doi.org/10.2174/1389557514666140820115052 |
Print ISSN 1389-5575 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5607 |
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