Silica Bound Sulphonic Acid Functionalized Imidazolium Ionic Liquid as a Recyclable and Recoverable Catalyst for N-Boc Protection of Amines

Title:Silica Bound Sulphonic Acid Functionalized Imidazolium Ionic Liquid as a Recyclable and Recoverable Catalyst for N-Boc Protection of Amines

Volume: 3 Issue: 3

Author(s): Amanpreet Kaur and Vasundhara Singh

Affiliation:

Keywords: Amines, N-Boc protection, organic-inorganic hybrid catalyst, sulphonic acid catalyst.

Abstract: In the present work, silica supported imidazolium based sulphonic acid was developed via a simple route as a hybrid organic-inorganic solid acid catalyst. The covalent anchoring to the silica support gave a stable catalyst in quantitative yield, while the ionic tag assisted in increasing the solubility of the reactants to facilitate the reaction under solventless conditions, being a homogeneous -heterogeneous catalytic system and having the distinct advantages of both. The catalytic efficacy of the solid acid catalyst was tested for the N-Boc protection of amines. The reactivity order followed by amines was aliphatic >aromatic> hetrocyclic>aminoalcohols. This efficient protocol has advantages of better workability of catalyst, reduced reaction time, improved yield, high TON and the catalyst is both recyclable and recoverable upto seven cycles.

Cite this article as:

Kaur Amanpreet and Singh Vasundhara, Silica Bound Sulphonic Acid Functionalized Imidazolium Ionic Liquid as a Recyclable and Recoverable Catalyst for N-Boc Protection of Amines, Current Catalysis 2014; 3 (3) . https://dx.doi.org/10.2174/2211544703666140812232332