Megaspinoxide A: New Norterpene Cyclic Peroxide from the Sponge Diacarnus megaspinorhabdosa

Title:Megaspinoxide A: New Norterpene Cyclic Peroxide from the Sponge Diacarnus megaspinorhabdosa

Volume: 4 Issue: 1

Author(s): Sabrin R.M. Ibrahim, Rwaida A. Al Haidari and Gamal A. Mohamed

Affiliation:

Keywords: Diacarnus megaspinorhabdosa, norsesterpene, megaspinoxide A, sigmosceptrellin B, nebularine, cytotoxic, antimicrobial.

Abstract: Re-investigation of the methanolic extract of the sponge Diacarnus megaspinorhabdosa afforded one new norsesterpene cyclic peroxide megaspinoxide A (2), together with two known compounds sigmosceptrellin B (1) and nebularine (3). The structures of the isolated compounds were established on the basis of one and two dimensional NMR spectroscopic studies (¹H, ¹³C, DEPT, COSY, HMQC, HMBC, and ROESY) as well as, mass spectral analysis. The isolated compounds were evaluated for their cytotoxic and antimicrobial activities.

Cite this article as:

R.M. Ibrahim Sabrin, A. Al Haidari Rwaida and A. Mohamed Gamal, Megaspinoxide A: New Norterpene Cyclic Peroxide from the Sponge Diacarnus megaspinorhabdosa, The Natural Products Journal 2014; 4(1) . https://dx.doi.org/10.2174/221031550401140715145414