Abstract
Mycobacterium fortuitum complex skin infection is described in a previously healthy adolescent girl in Sydney, Australia. Mycobacterium fortuitum typically causes superficial skin infections following trauma to the skin and in our patient may have been related to prior leg “waxing”. This case highlights common causes for a delay in diagnosis: lack of clinician awareness and inadequate microbiological and histopathological investigations of tissue samples. Due to the size and number of lesions, surgical excision was felt to be a less desirable therapeutic option due to the potential risk of poor cosmetic outcome for our patient. The standard chemotherapeutic approach to M. fortuitum infections involves the use of a combination of at least two antimicrobial agents to which the isolate is susceptible. Despite in vitro susceptibility testing that suggested that the isolate from our patient was resistant to most oral anti-microbial agents, our patient was treated successfully with a 10-week course of oral trimethoprim-sulfamethoxazole and moxifloxacin.
Keywords: Antibiotics, adolescent, granuloma, histopathology, Mycobacterium fortuitum, skin infection.
Infectious Disorders - Drug Targets
Title:Mycobacterium fortuitum Complex Skin Infection in a Healthy Adolescent
Volume: 14 Issue: 3
Author(s): Rebecca Sparks and Ameneh Khatami
Affiliation:
Keywords: Antibiotics, adolescent, granuloma, histopathology, Mycobacterium fortuitum, skin infection.
Abstract: Mycobacterium fortuitum complex skin infection is described in a previously healthy adolescent girl in Sydney, Australia. Mycobacterium fortuitum typically causes superficial skin infections following trauma to the skin and in our patient may have been related to prior leg “waxing”. This case highlights common causes for a delay in diagnosis: lack of clinician awareness and inadequate microbiological and histopathological investigations of tissue samples. Due to the size and number of lesions, surgical excision was felt to be a less desirable therapeutic option due to the potential risk of poor cosmetic outcome for our patient. The standard chemotherapeutic approach to M. fortuitum infections involves the use of a combination of at least two antimicrobial agents to which the isolate is susceptible. Despite in vitro susceptibility testing that suggested that the isolate from our patient was resistant to most oral anti-microbial agents, our patient was treated successfully with a 10-week course of oral trimethoprim-sulfamethoxazole and moxifloxacin.
Export Options
About this article
Cite this article as:
Sparks Rebecca and Khatami Ameneh, Mycobacterium fortuitum Complex Skin Infection in a Healthy Adolescent, Infectious Disorders - Drug Targets 2014; 14 (3) . https://dx.doi.org/10.2174/1871526514666140713163050
DOI https://dx.doi.org/10.2174/1871526514666140713163050 |
Print ISSN 1871-5265 |
Publisher Name Bentham Science Publisher |
Online ISSN 2212-3989 |
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
- Announcements
Related Articles
-
The Cancer Related Thrombotic Tendency in Sepsis
Current Drug Targets Inhibition of Quorum Sensing in Staphylococcus spp.
Current Pharmaceutical Design Novel Antimicrobial Agents Against Multi-drug-resistant Gram-positive Bacteria: An Overview
Recent Patents on Anti-Infective Drug Discovery Advances in Peptide Pharmaceuticals
Current Pharmaceutical Biotechnology Potential Therapeutic Application of Chondroitin Sulfate/Dermatan Sulfate
Current Drug Discovery Technologies <i>Corynebacterium Striatum</i>, an Emerging Nosocomial Pathogen: Case Reports
Infectious Disorders - Drug Targets Selection Criteria for Probiotics and Potential of Cereal Based Food Products as Novel Probiotic-Carriers
Current Nutrition & Food Science Waste Material of Propolis as a Film Forming Agent Intended to Modify the Metronidazole Release: Preparation and Characterization
Current Drug Delivery Protective Effects of Astaxanthin on Nephrotoxicity in Rats with Induced Renovascular Occlusion
Combinatorial Chemistry & High Throughput Screening Hallmarks in the Therapeutic Approach of Aortic Aneurysms: The Main Contributors
Current Pharmaceutical Design Imidazole Derivatives and their Antibacterial Activity - A Mini-Review
Mini-Reviews in Medicinal Chemistry Complications of Infective Endocarditis
Cardiovascular & Hematological Disorders-Drug Targets Prosthetic Devices with Nanostructurated Surfaces for Increased Resistance to Microbial Colonization
Current Pharmaceutical Biotechnology Buprenorphine and Buprenorphine/Naloxone Diversion, Misuse, and Illicit Use: An International Review
Current Drug Abuse Reviews Human Heart Failure: A Proteomics Perspective
Current Proteomics An Update to Enterococcal Bacteremia: Epidemiology, Resistance, and Outcome
Infectious Disorders - Drug Targets Pneumococcal Infections at Hajj: Current Knowledge Gaps
Infectious Disorders - Drug Targets Evaluation of Echocardiographic Abnormalities in HIV Positive Patients Treated with Antiretroviral Medications
Infectious Disorders - Drug Targets Uveitis in Rheumatic Diseases
Current Rheumatology Reviews Daptomycin: A Review of Properties, Clinical Use, Drug Delivery and Resistance
Mini-Reviews in Medicinal Chemistry