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Current Organic Synthesis

Editor-in-Chief

ISSN (Print): 1570-1794
ISSN (Online): 1875-6271

Synthesis of Allosamidin and its Analogues

Author(s): Gangliang Huang and Qilin Tang

Volume 11 , Issue 5 , 2014

Page: [696 - 700] Pages: 5

DOI: 10.2174/1570179411666140623223120

Price: $65

Abstract

The pseudo-trisaccharide allosamidin 1 is a potent inhibitor of all family 18 chitinases, and it is confirmed to have biological activities against insects and fungi. The solid/liquid phase syntheses of allosamidin 1 and its analogues have been developed in recent years, and these compounds can be obtained by iterative glycosylation reactions, catalytic hydrogenation, acetylation, deacetylation, or photolysis, respectively.

Keywords: Allosamidin, analogues, recent development, synthesis.

Graphical Abstract

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