Abstract
Benzocoumarins are coumarins with a phenyl group bonded to 3,4-, 5,6-, 6,7-, or 7,8-positions. Over the past years, significant efforts have been made not only to isolate the novel structural analogs of benzocoumarins with prominent bioactivities but also to design new synthetic methods to synthesize benzocoumarins with better or novel biological properties. The aim of this review is to provide the readers with an overview of the research progress of benzocoumarins from 1953 to May 2014, covering its isolation, synthesis, and biological activities.
Keywords: Benzocoumarins, biological activities, isolation, natural products, synthesis.
Mini-Reviews in Medicinal Chemistry
Title:Benzocoumarins: Isolation, Synthesis, and Biological Activities
Volume: 14 Issue: 7
Author(s): Hai-Ning Lv, Peng-Fei Tu and Yong Jiang
Affiliation:
Keywords: Benzocoumarins, biological activities, isolation, natural products, synthesis.
Abstract: Benzocoumarins are coumarins with a phenyl group bonded to 3,4-, 5,6-, 6,7-, or 7,8-positions. Over the past years, significant efforts have been made not only to isolate the novel structural analogs of benzocoumarins with prominent bioactivities but also to design new synthetic methods to synthesize benzocoumarins with better or novel biological properties. The aim of this review is to provide the readers with an overview of the research progress of benzocoumarins from 1953 to May 2014, covering its isolation, synthesis, and biological activities.
Export Options
About this article
Cite this article as:
Lv Hai-Ning, Tu Peng-Fei and Jiang Yong, Benzocoumarins: Isolation, Synthesis, and Biological Activities, Mini-Reviews in Medicinal Chemistry 2014; 14(7) . https://dx.doi.org/10.2174/1389557514666140622204608
DOI https://dx.doi.org/10.2174/1389557514666140622204608 |
Print ISSN 1389-5575 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5607 |

- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility Of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
- Announcements
- Forthcoming Thematic Issues
Related Articles
-
Clinical Considerations of Focal Drug Delivery in Cancer Treatment
Current Drug Delivery An Integrative “Omics” Approach, for Identification of Bona Fides PLK1 Associated Biomarker in Esophageal Adenocarcinoma
Current Cancer Drug Targets How Cancer Cells Resist Chemotherapy: Design and Development of Drugs Targeting Protein-Protein Interactions
Current Topics in Medicinal Chemistry The Therapeutic Target Hsp90 and Cancer Hallmarks
Current Pharmaceutical Design Bevacizumab and Angiogenesis Inhibitors in the Treatment of CNS Metastases: The Road less Travelled
Current Molecular Pharmacology In Silico ADME Prediction: Data Sets and Models
Current Computer-Aided Drug Design Recent Patents of Gene Sequences Relative to the Phosphatidylinositol 3-kinase / Akt Pathway and their Relevance to Drug Discovery
Recent Patents on DNA & Gene Sequences Gap Junctions as Targets for Cancer Chemoprevention and Chemotherapy
Current Drug Targets Antifungal Prophylaxis in the Neonatal Intensive Care Unit (NICU)
Current Pediatric Reviews Therapeutic Monoclonal Antibodies: Strategies and Challenges for Biosimilars Development
Current Medicinal Chemistry Exosomal miR-214-5p Released from Glioblastoma Cells Modulates Inflammatory Response of Microglia after Lipopolysaccharide Stimulation through Targeting CXCR5
CNS & Neurological Disorders - Drug Targets Monoclonal Antibodies: A Prospective and Retrospective View
Current Medicinal Chemistry Rasburicase: A New Approach for Preventing and/or Treating Tumor Lysis Syndrome
Current Pharmaceutical Design The Use of Lentinan for Treating Gastric Cancer
Anti-Cancer Agents in Medicinal Chemistry Modulators of Vascular Sex Hormone Receptors and their Effects in Estrogen-Deficiency States Associated with Menopause
Recent Patents on Cardiovascular Drug Discovery Patents and the Development on Polymer based Nanomaterial (PAMAM Dendrimer) for Biomedical Applications
Recent Patents on Biomedical Engineering (Discontinued) Stem Cells: In Sickness and in Health
Current Stem Cell Research & Therapy The Effect of Psychological Stress and Social Isolation on Neuroimmunoendocrine Communication
Current Pharmaceutical Design Aliphatic Nucleophilic Radiofluorination
Current Radiopharmaceuticals Cytotoxic and Chemopreventive Effects of Gemin D Against Different Mutagens Using In Vitro and In Vivo Assays
Anti-Cancer Agents in Medicinal Chemistry