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CNS & Neurological Disorders - Drug Targets

Editor-in-Chief

ISSN (Print): 1871-5273
ISSN (Online): 1996-3181

Current Directions in Non-Invasive Low Intensity Electric Brain Stimulation for Depressive Disorder

Author(s): Dennis J.L.G. Schutter and Alexander T. Sack

Volume 13 , Issue 6 , 2014

Page: [945 - 952] Pages: 8

DOI: 10.2174/1871527313666140612115123

Price: $65

Abstract

Non-invasive stimulation of the human brain to improve depressive symptoms is increasingly finding its way in clinical settings as a viable form of somatic treatment. Following successful modulation of neural excitability with subsequent antidepressant effects, neural polarization by administrating weak direct currents to the scalp has gained renewed interest. A new wave of basic and clinical studies seems to underscore the potential therapeutic value of direct current stimulation in the treatment of depression. Issues concerning the lack of mechanistic insights into the workings of modifying brain function through neural polarization and how this process translates to its antidepressant properties calls for additional research. The range of its clinical applicability has yet to be established.

Keywords: Depressive disorder, non-invasive brain stimulation, transcranial direct current stimulation, treatment.


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