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Inflammation & Allergy - Drug Targets (Discontinued)


ISSN (Print): 1871-5281
ISSN (Online): 2212-4055

Brain-Skin Connection: Stress, Inflammation and Skin Aging

Author(s): Ying Chen Chen and John Lyga

Volume 13, Issue 3, 2014

Page: [177 - 190] Pages: 14

DOI: 10.2174/1871528113666140522104422


The intricate relationship between stress and skin conditions has been documented since ancient times. Recent clinical observations also link psychological stress to the onset or aggravation of multiple skin diseases. However, the exact underlying mechanisms have only been studied and partially revealed in the past 20 years or so. In this review, the authors will discuss the recent discoveries in the field of “Brain-Skin Connection”, summarizing findings from the overlapping fields of psychology, endocrinology, skin neurobiology, skin inflammation, immunology, and pharmacology.

Keywords: Inflammation, skin aging, stress response.

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