Generic placeholder image

Current Pharmaceutical Biotechnology


ISSN (Print): 1389-2010
ISSN (Online): 1873-4316

Research Article

MicroRNAs: A Novel Non-Invasive Biomarker for Patients with Urological Malignancies

Author(s): Jorg Ellinger and Stefan C. Muller

Volume 15, Issue 5, 2014

Page: [486 - 491] Pages: 6

DOI: 10.2174/1389201015666140519124909

Price: $65


MicroRNAs are small non-coding RNA molecules which do not code for proteins, but control the expression of a significant proportion of the genome. The microRNA expression differences of normal and malignant tissue, as well as the differences in various tumor entities qualify this RNA species as biomarker for cancer patients. The detection of microRNAs in various bodily fluids stimulated research, and it was demonstrated for most human malignancies that tumorassociated microRNAs are detectable in patients circulation, thereby providing diagnostic and/or prognostic information.

Keywords: Biomarker, bladder cancer, diagnosis, microRNA, prostate cancer, renal cell carcinoma, testicular cancer.

Rights & Permissions Print Cite
© 2024 Bentham Science Publishers | Privacy Policy