Abstract
Breast cancer and prostate cancer are the most common invasive types of cancers in women and men. Many of the recent advances in understanding the pathophysiology of breast and prostate cancers have paved the way for new treatment strategies. The alarming increase in the global cancer death toll has fueled the quest for new effective anti-tumor drugs through biological screening of both terrestrial and marine organisms. Recently, marine-derived natural bioactive products, isolated from aquatic fungi, cyanobacteria, sponges, algae, and tunicates, have been found to exhibit various anti-cancer activities including anti-angiogenic, anti-proliferative, inhibition of topoisomerase activities and induction of apoptosis. Thus, marine derived chemical derivatives such as alkaloids, macrolides, terpenes and other miscellaneous compounds possess anticancer properties. Hence, this review discusses the role of marine compounds on breast and prostate cancer.
Keywords: Alkaloids, breast, cancer, macrolides, prostate, spongistatin.
Current Bioactive Compounds
Title:Marine Derived Bioactive Compounds for Breast and Prostate Cancer Treatment: A Review
Volume: 10 Issue: 1
Author(s): Senthilkumar Kalimuthu, Jayachandran Venkatesan and Se-Kwon Kim
Affiliation:
Keywords: Alkaloids, breast, cancer, macrolides, prostate, spongistatin.
Abstract: Breast cancer and prostate cancer are the most common invasive types of cancers in women and men. Many of the recent advances in understanding the pathophysiology of breast and prostate cancers have paved the way for new treatment strategies. The alarming increase in the global cancer death toll has fueled the quest for new effective anti-tumor drugs through biological screening of both terrestrial and marine organisms. Recently, marine-derived natural bioactive products, isolated from aquatic fungi, cyanobacteria, sponges, algae, and tunicates, have been found to exhibit various anti-cancer activities including anti-angiogenic, anti-proliferative, inhibition of topoisomerase activities and induction of apoptosis. Thus, marine derived chemical derivatives such as alkaloids, macrolides, terpenes and other miscellaneous compounds possess anticancer properties. Hence, this review discusses the role of marine compounds on breast and prostate cancer.
Export Options
About this article
Cite this article as:
Kalimuthu Senthilkumar, Venkatesan Jayachandran and Kim Se-Kwon, Marine Derived Bioactive Compounds for Breast and Prostate Cancer Treatment: A Review, Current Bioactive Compounds 2014; 10 (1) . https://dx.doi.org/10.2174/1573407210666140327212945
DOI https://dx.doi.org/10.2174/1573407210666140327212945 |
Print ISSN 1573-4072 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-6646 |
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
- Announcements
Related Articles
-
Antiangiogenesis and Radiotherapy: What Is the Role of Combined Modality Treatment?
Current Medicinal Chemistry - Anti-Cancer Agents Inhibition of Protein Kinase c-Src as a Therapeutic Approach for Cancer and Bone Metastases
Anti-Cancer Agents in Medicinal Chemistry Synthetic Lethal Interactions in Cancer Therapy
Current Cancer Drug Targets Epigenetic Regulation of ABCB1 Transporter Expression and Function
Current Pharmacogenomics and Personalized Medicine Proteomics Approach to Illustrate Drug Action Mechanisms
Current Drug Discovery Technologies Chemistry and Biological Activities of 1,3-Benzothiazoles
Mini-Reviews in Organic Chemistry Monoclonal Antibodies: A Review
Current Clinical Pharmacology Dietary Phytochemicals and Endrocrine-related Activities: An Update
Mini-Reviews in Medicinal Chemistry A New Antitumor Agent, (3-chloro-7-methoxyfuro[2,3-b]-quinolin-4-yl)-(4-methoxyphenyl) amine, Loaded in Solid Lipid Nanoparticles: Characterization and Pharmacokinetics
Current Nanoscience Improved Immunogenicity Against a Her2/neu-Derived Peptide by Employment of a Pan HLA DR-Binding Epitope and CpG in a BALB/c Mice Model
Anti-Cancer Agents in Medicinal Chemistry Pattern Recognition by CD6: A Scavenger-Like Lymphocyte Receptor
Current Drug Targets Tools For Decision-Making In Older Cancer Patients. Role Of The Comprehensive Geriatric Assessment
Anti-Cancer Agents in Medicinal Chemistry Status Quo in Antibody-Drug Conjugates - Can Glyco- Enzymes Solve the Current Challenges?
Protein & Peptide Letters Serum HE4 Level as a Biomarker to Predict the Recurrence of Gynecologic Cancers
Current Drug Targets Proteomic Level Changes on Treatment in MCF-7/DDP Breast Cancer Drug- Resistant Cells
Anti-Cancer Agents in Medicinal Chemistry The Effect of Psychological Stress and Social Isolation on Neuroimmunoendocrine Communication
Current Pharmaceutical Design The Roles of Mesenchymal Stem Cells in Tissue Repair and Disease Modification
Current Stem Cell Research & Therapy Synthesis and Biological Evaluation of Some Novel Thiazolylhydrazinomethylideneferrocenes as Antimicrobial Agents
Letters in Drug Design & Discovery BACE1 Dependent Neuregulin Processing: Review
Current Alzheimer Research An Update on Natural Occurrence and Biological Activity of Chromones
Current Medicinal Chemistry