Abstract
Postoperative delirium may occur as a serious complication after orthopedic surgery. In addition, risk factors such as age, mental and organic illnesses may increase the incidence of the aforementioned complication. Delirium has a negative impact on postoperative mobilization and recovery. Furthermore, it may result in longer hospital treatment. This study is a systematic literature review of articles that was conducted through a key word search of PubMed. The review includes: 1) pathogenesis, 2) risk factors in the development of postoperative delirium, and 3) the effective methods and strategies of treatment, especially in relation to patients hospitalized in orthopedics.
This systematic review will discuss benzodiazepines and haloperidol, which are used to treat delirium in the prevention and treatment of postoperative delirium. The findings suggest that prevention of postoperative delirium with drugs can be an effective strategy.
Keywords: Benzodiazepines, haloperidol, hip fracture, olanzapine, orthopedic, postoperative delirium.
Current Psychopharmacology
Title:Use of Benzodiazepines and Haloperidol Among Orthopedic Patients in Postoperative Delirium. A Systematic Review
Volume: 3
Author(s): Mateusz Szymczak, Joanna Iskra-Trifunovic, Anna Grzywacz, Jerzy Samochowiec and Lukasz Kolodzie
Affiliation:
Keywords: Benzodiazepines, haloperidol, hip fracture, olanzapine, orthopedic, postoperative delirium.
Abstract: Postoperative delirium may occur as a serious complication after orthopedic surgery. In addition, risk factors such as age, mental and organic illnesses may increase the incidence of the aforementioned complication. Delirium has a negative impact on postoperative mobilization and recovery. Furthermore, it may result in longer hospital treatment. This study is a systematic literature review of articles that was conducted through a key word search of PubMed. The review includes: 1) pathogenesis, 2) risk factors in the development of postoperative delirium, and 3) the effective methods and strategies of treatment, especially in relation to patients hospitalized in orthopedics.
This systematic review will discuss benzodiazepines and haloperidol, which are used to treat delirium in the prevention and treatment of postoperative delirium. The findings suggest that prevention of postoperative delirium with drugs can be an effective strategy.
Export Options
About this article
Cite this article as:
Szymczak Mateusz, Iskra-Trifunovic Joanna, Grzywacz Anna, Samochowiec Jerzy and Kolodzie Lukasz, Use of Benzodiazepines and Haloperidol Among Orthopedic Patients in Postoperative Delirium. A Systematic Review, Current Psychopharmacology 2014; 3 (1) . https://dx.doi.org/10.2174/2211556003666140212211434
DOI https://dx.doi.org/10.2174/2211556003666140212211434 |
Print ISSN 2211-5560 |
Publisher Name Bentham Science Publisher |
Online ISSN 2211-5579 |
Call for Papers in Thematic Issues
Breakthroughs in drug design, development and delivery system for the management of neuro-psychiatric disorders
Neuropsychiatric diseases are one of the main causes of disability, affecting millions of people. Various drugs are used for its treatment, although no effective therapy has been found yet. The blood brain barrier (BBB) significantly complicates drugs delivery to the target cells in the brain tissues. This proposal describes the ...read more
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
- Announcements
Related Articles
-
Organic Toxins as Tools to Understand Ion Channel Mechanisms and Structure
Current Topics in Medicinal Chemistry A2A Adenosine Receptor and its Modulators: Overview on a Druggable GPCR and on Structure-Activity Relationship Analysis and Binding Requirements of Agonists and Antagonists
Current Pharmaceutical Design Ranolazine and its Antiarrhythmic Actions
Cardiovascular & Hematological Agents in Medicinal Chemistry Autoimmune Neuromuscular Disorders
Current Neuropharmacology Mineralocorticoid Antagonists in ESRD: An Overview of Clinical Trial Evidence
Current Vascular Pharmacology Prevalence, Presentation and Outcome of Secondary Bloodstream Infections among COVID-19 Patients
Infectious Disorders - Drug Targets Peripartum Cardiomyopathy: Current State of Knowledge, New Developments and Future Directions
Current Cardiology Reviews Meet Our Editorial Board Member
Current Pharmaceutical Biotechnology Therapy in Prion Diseases
Current Topics in Medicinal Chemistry Peptides in Oral Diseases
Current Pharmaceutical Design DL-3-n-Butylphthalide, an Anti-Oxidant Agent, Prevents Neurological Deficits and Cerebral Injury Following Stroke per Functional Analysis, Magnetic Resonance Imaging and Histological Assessment
Current Neurovascular Research The Use of Echocardiography in the Critically Ill; The Role of FADE (Fast Assessment Diagnostic Echocardiography) Training
Current Cardiology Reviews Brain Perfusion In Sepsis
Current Vascular Pharmacology Melanocortins in the Treatment of Male and Female Sexual Dysfunction
Current Topics in Medicinal Chemistry Novel Insight into the Inflammatory and Cellular Responses Following Experimental Glaucoma Surgery: A Roadmap for Inhibiting Fibrosis
Current Molecular Medicine Scope and Limitations of The Co-Drug Approach to Topical Drug Delivery
Current Pharmaceutical Design An Overview of Phytochemical and Pharmacological Profile of <i>Morus alba</i> Linn
Current Bioactive Compounds Aliskiren, a Direct Renin Inhibitor, in Clinical Practice: A New Approach in the Treatment of Hypertension
Current Vascular Pharmacology Reducing the Risk of Major Elective Non-cardiac Surgery: Is there a Role for Levosimendan in the Preoperative Optimization of Cardiac Function?
Current Drug Targets Sepsis, Coagulation and Anticoagulants
Endocrine, Metabolic & Immune Disorders - Drug Targets