Abstract
Many drugs may induce psoriatic lesions or exacerbate preexisting psoriasis. We report an exceptional case of psoriasis vulgaris probably induced by clarithromycin. A 37-year-old man was prescribed for pharyngitis clarithromycin 500mg twice a day. On the third day of treatment, he presented a non pruriginous erythemato-squamous eruption, of trunk and limbs. Skin biopsy showed a typical aspect of psoriasis vulgaris. The drug was interrupted and the patient was treated by topical corticoids with rapid improvement.
Keywords: Adverse drug reaction, clarithromycin, psoriasis.
Current Drug Safety
Title:Clarithromycin Induced Psoriasis in a 37-Year Old Man
Volume: 9 Issue: 1
Author(s): Ahmed Zaiem, Amel Mebazaa, Ghozlane Lakhoua, Talel Badri, Rym Sahnoun, Sarrah Kastalli, Riadh Daghfous and Sihem El Aidli
Affiliation:
Keywords: Adverse drug reaction, clarithromycin, psoriasis.
Abstract: Many drugs may induce psoriatic lesions or exacerbate preexisting psoriasis. We report an exceptional case of psoriasis vulgaris probably induced by clarithromycin. A 37-year-old man was prescribed for pharyngitis clarithromycin 500mg twice a day. On the third day of treatment, he presented a non pruriginous erythemato-squamous eruption, of trunk and limbs. Skin biopsy showed a typical aspect of psoriasis vulgaris. The drug was interrupted and the patient was treated by topical corticoids with rapid improvement.
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Zaiem Ahmed, Mebazaa Amel, Lakhoua Ghozlane, Badri Talel, Sahnoun Rym, Kastalli Sarrah, Daghfous Riadh and Aidli El Sihem, Clarithromycin Induced Psoriasis in a 37-Year Old Man, Current Drug Safety 2014; 9 (1) . https://dx.doi.org/10.2174/1574886308666140110123256
DOI https://dx.doi.org/10.2174/1574886308666140110123256 |
Print ISSN 1574-8863 |
Publisher Name Bentham Science Publisher |
Online ISSN 2212-3911 |
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