Abstract
The Wnt signaling pathway is one of the crucial signaling pathways that regulate many aspects of central nervous system. In this review, we tempt to depict an overall picture of the Wnt signaling with its multitude of roles in schizophrenia. If the Wnt signaling pathway plays a crucial role in the pathogenesis of schizophrenia as we suggest, a better understanding of the Wnt pathway might contribute to developing new and more effective tools for diagnosis and treatment of schizophrenia.
Keywords: Adenomatous polyposis coli, glycogen synthase kinase-3, schizophrenia, Wnt signaling pathway.
CNS & Neurological Disorders - Drug Targets
Title:Wnt Signaling Pathway in Schizophrenia
Volume: 13 Issue: 5
Author(s): Yanmin Peng, Yifeng Xu and Donghong Cui
Affiliation:
Keywords: Adenomatous polyposis coli, glycogen synthase kinase-3, schizophrenia, Wnt signaling pathway.
Abstract: The Wnt signaling pathway is one of the crucial signaling pathways that regulate many aspects of central nervous system. In this review, we tempt to depict an overall picture of the Wnt signaling with its multitude of roles in schizophrenia. If the Wnt signaling pathway plays a crucial role in the pathogenesis of schizophrenia as we suggest, a better understanding of the Wnt pathway might contribute to developing new and more effective tools for diagnosis and treatment of schizophrenia.
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Cite this article as:
Peng Yanmin, Xu Yifeng and Cui Donghong, Wnt Signaling Pathway in Schizophrenia, CNS & Neurological Disorders - Drug Targets 2014; 13 (5) . https://dx.doi.org/10.2174/1871527312666131223113521
DOI https://dx.doi.org/10.2174/1871527312666131223113521 |
Print ISSN 1871-5273 |
Publisher Name Bentham Science Publisher |
Online ISSN 1996-3181 |
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