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Current Organic Chemistry

Editor-in-Chief

ISSN (Print): 1385-2728
ISSN (Online): 1875-5348

Ytterbium Triflate: A Versatile Catalyst in Organic Synthesis

Author(s): Lang-Jun Zhang, He-Lin Lu, Zong-Wen Wu and Yun-Sheng Huang

Volume 17, Issue 23, 2013

Page: [2906 - 2920] Pages: 15

DOI: 10.2174/138527281723131218135830

Price: $65

Abstract

Ytterbium triflate, Yb(OTf)3, is a versatile Lewis acid that has high catalytic activity in many organic reactions, including aldol, Michael, Mannich, Friedel-Crafts, Diels-Alder, and some other types of reactions. Less than 10 mol% of Yb(OTf)3 is normally sufficient for most organic transformations and can be recovered and re-used without loss of catalytic activity. In addition, Yb(OTf)3 is very stable and its catalyzed reactions can be carried out in both organic solvents and aqueous conditions.

Keywords: Ytterbium triflate, Catalyst, Aldol condensation, Michael addition, Mannich reaction, Friedel-crafts, Diels-alder.


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