Potential Effects of Cannabidiol as a Wake-Promoting Agent

Title:Potential Effects of Cannabidiol as a Wake-Promoting Agent

Volume: 12 Issue: 3

Author(s): Eric Murillo-Rodriguez, Andrea Sarro-Ramirez, Daniel Sanchez, Stephanie Mijangos-Moreno, Alma Tejeda-Padron, Alwin Poot-Ake, Khalil Guzman, Elda Pacheco-Pantoja and Oscar Arias-Carrion

Affiliation:

• Laboratorio de Neurociencias Moleculares e Integrativas, Escuela de Medicina, Division Ciencias de la Salud, Universidad Anahuac Mayab, Carretera Merida-Progreso Km, 15.5, A.P. 96 Cordemex C.P. 97310, Merida, Yucatan, Mexico.,Mexico

Keywords: Dopamine, hypothalamus, marijuana, sleep, sleepiness.

Abstract: Over the last decades, the scientific interest in chemistry and pharmacology of cannabinoids has increased. Most attention has focused on Δ⁹-tetrahydrocannabinol (Δ⁹-THC) as it is the psychoactive constituent of Cannabis sativa (C. sativa). However, in previous years, the focus of interest in the second plant constituent with non-psychotropic properties, cannabidiol (CBD) has been enhanced. Recently, several groups have investigated the pharmacological properties of CBD with significant findings; furthermore, this compound has raised promising pharmacological properties as a wake-inducing drug. In the current review, we will provide experimental evidence regarding the potential role of CBD as a wake-inducing drug.

Cite this article as:

Murillo-Rodriguez Eric, Sarro-Ramirez Andrea, Sanchez Daniel, Mijangos-Moreno Stephanie, Tejeda-Padron Alma, Poot-Ake Alwin, Guzman Khalil, Pacheco-Pantoja Elda and Arias-Carrion Oscar, Potential Effects of Cannabidiol as a Wake-Promoting Agent, Current Neuropharmacology 2014; 12(3) . https://dx.doi.org/10.2174/1570159X11666131204235805