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Letters in Organic Chemistry


ISSN (Print): 1570-1786
ISSN (Online): 1875-6255

1,2,4-Triazoles: A Review of Synthetic Approaches and the Biological Activity

Author(s): Suresh Maddila, Ramakanth Pagadala and Sreekanth B. Jonnalagadda

Volume 10, Issue 10, 2013

Page: [693 - 714] Pages: 22

DOI: 10.2174/157017861010131126115448


1,2,4-Triazoles and their derivatives have a distinct place in the field of medicinal and pharmaceutical chemistry. These are used as lead compounds for the synthesis of numerous heterocyclic compounds which possess diverse biological activities and play pivotal roles. This review covers the latest literature and knowledge on the synthetic procedures for various triazoles derivatives, their activities and pharmacological applications.

Keywords: 1, 2, 4-Traizole, synthesis, biological activity, review.

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