Highly Efficient and Selective Addition of Hydroxylamine to Nitriles in Ionic Liquids

After the discovery in 1990, bioorthogonal chemistry encompassed a set of diverse, fast-paced selective chemical reactions, facilitating the study of biomolecules under physiological aura without intervening in the biochemical processes. Over the past two decades, significant progress has been witnessed in bioorthogonal reactions such as Staudinger ligation, metal-catalyzed coupling reactions, ...read more

The development of new green pesticides is currently one of the hotspots in the field of pesticide research, aiming to develop efficient, environmentally friendly, and safe pesticide products to meet the needs of modern agricultural production. New green pesticides prioritize environmental friendliness and ecological safety. Therefore, during the research and ...read more

Organic synthesis is a fundamental discipline in chemistry, which is crucial for the creation of complex molecules with diverse applications in pharmaceuticals, materials science, and beyond. However, the process of designing efficient synthetic routes for target molecules remains challenging. Chemical graph theory, a branch of theoretical chemistry, offers powerful tools ...read more

This proposal aims to explore the integration of computational graph theory into organic synthesis. By representing chemical compounds and reactions as graphs, we can enhance our understanding of reaction mechanisms, predict synthetic pathways, and optimize reaction conditions. This research will focus on developing algorithms that utilize graph theory to streamline ...read more