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Current Organic Chemistry


ISSN (Print): 1385-2728
ISSN (Online): 1875-5348

Emerging Electrical Biosensors for Detecting Pathogens and Antimicrobial Susceptibility Tests

Author(s): Pei-Wen Yen, Yen-Pei Lu, Chih-Ting Lin, Chi-Hung Hwang, J. Andrew Yeh, Ming-Yu Lin and Keng-Shiang Huang

Volume 18, Issue 2, 2014

Page: [165 - 172] Pages: 8

DOI: 10.2174/13852728113176660140

Price: $65


The past decade has witnessed the development of innovative biosensing technologies for detecting pathogens, and evaluating the anti-microbial susceptibility test in the infectious diseases. Recent advances in the field have been focused on the development of miniaturized biosensors with high sensitivity, specificity and stability. Possibility for commercialization is also a key criterion to develop biosensors in reality. In this article, we introduced several electrical-based biosensors with prospective for commercialization. To have an in-field detection for pathogens, the electrical biosensor is promising because of its ease to be implemented with micro/nano fabrication technologies. Several electrical biosensing techniques, such as ion-sensitive field effect transistor, nanowire, and microcantilever have been introduced. In addition, advantages and achievements of each electrical biosensing technique have also been reviewed.

Keywords: Pathogens, Electrical biosensors, Human immunodeficiency virus (HIV), Tuberculosis (TB), group B Streptococcus (GBS), methicillin-resistant Staphylococcus aureus (MRSA).

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