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Medicinal Chemistry

Editor-in-Chief

ISSN (Print): 1573-4064
ISSN (Online): 1875-6638

Review Article

Chemistry, Stability and Bioavailability of Resveratrol

Author(s):

Volume 10, Issue 3, 2014

Page: [237 - 245] Pages: 9

DOI: 10.2174/15734064113096660053

Price: $65

Abstract

Resveratrol is a bioactive polyphenol found in many vegetables. It is well known for its multiple pharmacological activities, such as anti-inflammatory, antioxidant, antimicrobial, anticancer, neuroprotective and cardioprotective effects. In vitro evidence of resveratrol efficacy is widespread, however, many concerns regarding its effectiveness in vivo arise from its poor stability in vitro and bioavailability following oral ingestion. This review focuses on the in vitro stability, with special focus on the photochemical stability of resveratrol, and on the therapeutic perspectives of this molecule due to its low bioavailability.

Keywords: Bioavailability, isomerisation, oxidation, phenantrenic derivatives, photochemical reactions, resveratrol.

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