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Current Pharmaceutical Design

Editor-in-Chief

ISSN (Print): 1381-6128
ISSN (Online): 1873-4286

Schizophrenia: Causes and Treatments

Author(s): Zafar U. Khan, Elisa Martin-Montañez and E. Chris Muly

Volume 19, Issue 36, 2013

Page: [6451 - 6461] Pages: 11

DOI: 10.2174/1381612811319360006

Price: $65

Abstract

Schizophrenia is a major mental illness that is characterized by psychosis, apathy, social withdrawal and cognitive impairment. These abnormalities in patients results in impaired functioning in work, school, parenting, self-care, independent living, interpersonal relationships, and leisure. Although the search for the biological correlates of schizophrenia has met with limited success, new advances in genetics and pharmacology are promising. Here, we describe the symptoms, causes, diagnosis, strategies for treatment, and clinical impact of the currently available medications.

Keywords: Positive symptoms, negative symptoms, cognitive symptoms, brain circuits, dopamine, glutamate, genes, environmental factors, clinical criterias, imaging, typical antipsychotics, atypical antipsychotics.


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