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Current Pharmaceutical Design

Editor-in-Chief

ISSN (Print): 1381-6128
ISSN (Online): 1873-4286

Acute and Long-Term Effects of Cannabis Use: A Review

Author(s): Laurent Karila, Perrine Roux, Benjamin Rolland, Amine Benyamina, Michel Reynaud, Henri-Jean Aubin and Christophe Lancon

Volume 20, Issue 25, 2014

Page: [4112 - 4118] Pages: 7

DOI: 10.2174/13816128113199990620

Price: $65

Abstract

Cannabis remains the most commonly used and trafficked illicit drug in the world. Its use is largely concentrated among young people (15- to 34-year-olds). There is a variety of cannabis use patterns, ranging from experimental use to dependent use. Men are more likely than women to report both early initiation and frequent use of cannabis. Due to the high prevalence of cannabis use, the impact of cannabis on public health may be significant. A range of acute and chronic health problems associated with cannabis use has been identified.

Cannabis can frequently have negative effects in its users, which may be amplified by certain demographic and/or psychosocial factors. Acute adverse effects include hyperemesis syndrome, impaired coordination and performance, anxiety, suicidal ideations/tendencies, and psychotic symptoms. Acute cannabis consumption is also associated with an increased risk of motor vehicle crashes, especially fatal collisions. Evidence indicates that frequent and prolonged use of cannabis can be detrimental to both mental and physical health. Chronic effects of cannabis use include mood disorders, exacerbation of psychotic disorders in vulnerable people, cannabis use disorders, withdrawal syndrome, neurocognitive impairments, cardiovascular and respiratory and other diseases.

Keywords: Cannabis, marijuana, cannabinoids, dependence, addiction, THC, acute effects, long-term effects, and cannabis use disorders.

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