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Protein & Peptide Letters


ISSN (Print): 0929-8665
ISSN (Online): 1875-5305

Influence of Selected Factors on Veins' Permeability for Albumin In Vitro

Author(s): Barbara Dolinska, Artur Caban, Lech Cierpka and Florian Ryszka

Volume 21, Issue 1, 2014

Page: [39 - 44] Pages: 6

DOI: 10.2174/09298665113209990082

Price: $65


We present the results of a study on the influence of albumin and prolactin concentrations and intravascular fluid pH on vein permeability for albumin. Permeability conditions were simulated depending on albumin concentration, pH value and prolactin concentration. In research model an in vitro method was applied using natural membrane - porcine vena cava inferior. Vein permeability was in the 0.63% to 5.69% range. In control variant permeability was ~2.54% and increased ~2 fold at decreased albumin and PRL concentrations. At increased albumin concentration permeability was decreased 4-fold. Albumin concentration significantly influences albumin permeability.

Keywords: Albumin, in vitro, permeability, prolactin, veins.

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