Abstract
There is no sense organ specifically dedicated to time perception, as there is for other senses such as hearing and vision. However, this subjective sense of time is fundamental to our conception of reality and it creates the temporal course of events in our lives. Here, we explored neurobiological relations from the clinical perspective, examining timing ability in patients with different neurological and psychiatric conditions (e.g. Parkinson’s disease, depression, bipolar disorder, anxiety disorders and schizophrenia). The neural bases of present distortions in time perception and temporal information processing still remain poorly understood. We reviewed: a) how the brain is capable of encoding time in different environments and multiple tasks, b) different models of interval timing, c) brain structures and neurotransmitters associated with time perception, d) the relationship between memory and time perception, e) neural mechanisms underlying different theories in neural and mental processes, and f) the relationship between different mental diseases and time perception. Bibliographic research was conducted based on publications over the past thirteen years written in English in the databases Scielo, Pubmed/MEDLINE, ISI Web of Knowledge. The time perceptions research are executed to evaluate time perception in mental diseases and can provide evidence for future clinical applications.
Keywords: Anxiety, mood, schizophrenia, Parkinson’s disease, time perception, timing, interval-timing.
CNS & Neurological Disorders - Drug Targets
Title:Time Perception Distortion in Neuropsychiatric and Neurological Disorders
Volume: 12 Issue: 5
Author(s): Luciano L. Menegaldo, Oscar Arias-Carrion, Pedro Ribeiro, Elzbieta Szelag, Yan Bao, Ernst Poppel, Antonio E. Nardi, Mauricio Cagy, Mohamed Salama, Silmar Teixeira, Renato Anghinah, Daniel Minc, Antonio L. Sanfim, Julio Guilherme Silva, Bruna Velasques, Flavia Paes and Sergio Machado
Affiliation:
Keywords: Anxiety, mood, schizophrenia, Parkinson’s disease, time perception, timing, interval-timing.
Abstract: There is no sense organ specifically dedicated to time perception, as there is for other senses such as hearing and vision. However, this subjective sense of time is fundamental to our conception of reality and it creates the temporal course of events in our lives. Here, we explored neurobiological relations from the clinical perspective, examining timing ability in patients with different neurological and psychiatric conditions (e.g. Parkinson’s disease, depression, bipolar disorder, anxiety disorders and schizophrenia). The neural bases of present distortions in time perception and temporal information processing still remain poorly understood. We reviewed: a) how the brain is capable of encoding time in different environments and multiple tasks, b) different models of interval timing, c) brain structures and neurotransmitters associated with time perception, d) the relationship between memory and time perception, e) neural mechanisms underlying different theories in neural and mental processes, and f) the relationship between different mental diseases and time perception. Bibliographic research was conducted based on publications over the past thirteen years written in English in the databases Scielo, Pubmed/MEDLINE, ISI Web of Knowledge. The time perceptions research are executed to evaluate time perception in mental diseases and can provide evidence for future clinical applications.
Export Options
About this article
Cite this article as:
Menegaldo L. Luciano, Arias-Carrion Oscar, Ribeiro Pedro, Szelag Elzbieta, Bao Yan, Poppel Ernst, Nardi E. Antonio, Cagy Mauricio, Salama Mohamed, Teixeira Silmar, Anghinah Renato, Minc Daniel, Sanfim L. Antonio, Silva Guilherme Julio, Velasques Bruna, Paes Flavia and Machado Sergio, Time Perception Distortion in Neuropsychiatric and Neurological Disorders, CNS & Neurological Disorders - Drug Targets 2013; 12(5) . https://dx.doi.org/10.2174/18715273113129990080
DOI https://dx.doi.org/10.2174/18715273113129990080 |
Print ISSN 1871-5273 |
Publisher Name Bentham Science Publisher |
Online ISSN 1996-3181 |

- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility Of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
- Announcements
- Forthcoming Thematic Issues
Related Articles
-
Small Neuroscience: The Nanostructure of the Central Nervous System and Emerging Nanotechnology Applications
Current Nanoscience EXTraordinary Bones: Functional and Genetic Analysis of the EXT Gene Family
Current Genomics Posture and Gait Biomechanical Aspects during Pregnancy and the Importance of Therapeutic Exercise: Literature Review
Current Women`s Health Reviews Cellular Cholesterol Efflux Pathways: Impact on Intracellular Lipid Trafficking and Methodological Considerations
Current Pharmaceutical Biotechnology Adenosine A2A Receptor Antagonists and Parkinsons Disease: State of the Art and Future Directions
Current Pharmaceutical Design Glutaminase Isoenzymes as Key Regulators in Metabolic and Oxidative Stress Against Cancer
Current Molecular Medicine Fluorescence Imaging in Cancerology
Current Molecular Imaging (Discontinued) Opposing Gatekeepers of Apical Sterol Transport: Niemann-Pick C1-Like 1 (NPC1L1) and ATP-Binding Cassette Transporters G5 and G8 (ABCG5/ABCG8)
Immunology, Endocrine & Metabolic Agents in Medicinal Chemistry (Discontinued) Melatonin Therapy of Pediatric Sleep Disorders: Recent Advances, Why it Works, Who are the Candidates and How to Treat
Current Pediatric Reviews Simvastatin and Other HMG-CoA Reductase Inhibitors on Brain Cholesterol Levels in Alzheimers Disease
Current Alzheimer Research The Role of Redox Dysregulation in the Inflammatory Response to Acute Myocardial Ischaemia-reperfusion Injury - Adding Fuel to the Fire
Current Medicinal Chemistry Protein Domains as Information Processing Units
Current Protein & Peptide Science Structure-Based β-Secretase (BACE1) Inhibitors
Current Pharmaceutical Design Sleep Disturbances and Cognitive Impairment in the Course of Type 2 Diabetes-A Possible Link
Current Neuropharmacology Isolation and Phenotypic Characterisation of Stem Cells from Late Stage Osteoarthritic Mesenchymal Tissues
Current Stem Cell Research & Therapy Pathological Gambling in Parkinson’s Disease: An Update on Medical Management
Current Psychopharmacology Current Role and Future Perspectives of Radioiodinated MIBG in the Evaluation of Dementia with Lewy Bodies
Current Radiopharmaceuticals 8-Hydroxyquinoline and Hydroxamic Acid Inhibitors of Botulinum Neurotoxin BoNT/A
Current Topics in Medicinal Chemistry Antidepressant Like Effects of Alternanthera sessilis and Clerodendrum infortunatum Leaves Extract in Immobility Models
The Natural Products Journal Shutting Down the Furnace: Preferential Killing of Cancer Cells with Mitochondrial-Targeting Molecules
Current Medicinal Chemistry