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Letters in Organic Chemistry


ISSN (Print): 1570-1786
ISSN (Online): 1875-6255

Development of Safe and Economical Synthesis of Isoxazole

Author(s): Lakshmikant H. Nitlikar and Devanand B. Shinde

Volume 10, Issue 9, 2013

Page: [637 - 639] Pages: 3

DOI: 10.2174/15701786113109990032

Price: $65


Isoxazole is a five membered heterocyclic compound having various pharmacological actions. The new practical synthesis of isoxazole from the easily available malonadehyde tetraethyl acetal by avoiding the use of toxic reagent such as cadmium chloride under environment friendly conditions has been developed.

Keywords: Isoxazole, Malonaldehyde tetraethyl acetal, di (1, 3-dioxolan-2-yl) methane.

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