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Current Medicinal Chemistry


ISSN (Print): 0929-8673
ISSN (Online): 1875-533X

Drug-Delivery Systems of Green Tea Catechins for Improved Stability and Bioavailability

Author(s): C. F. Rodrigues, K. Ascenção, F. A.M. Silva, B. Sarmento, M. B.P.P. Oliveira and J. C. Andrade

Volume 20, Issue 37, 2013

Page: [4744 - 4757] Pages: 14

DOI: 10.2174/09298673113209990158

Price: $65


Numerous studies in humans, animal models and cell lines have suggested the potential benefits from the consumption of green tea polyphenols, including prevention of cancer and heart diseases. However these potential effects have been strongly limited by green tea catechins low bioavailability, which hinders the development of therapeutic applications. In this review formulations that are being proposed for delivery of green tea catechins are discussed. New delivery systems are presented as valid alternatives to overcome the limitations such as green tea catechins poor stability or intestinal absorption.

Keywords: Antioxidant, drug delivery, epigallocatechin-3-gallate, green tea polyphenols, catechins, EGCG.

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