Abstract
There are different opinions on a possible sex bias in diabetes. In Sweden we have access to data since the 1930s, making it an ideal model. We aimed to study gender differences and time trends in the incidence and prevalence of type 1 diabetes in Sweden. We found 31 articles on incidence and 8 on prevalence (6 overlapping). Times series on incidence were found regarding children 0–15 years of age (with the Swedish Childhood Diabetes Registry, SCDR, since 1977), with up to 14,721 children with diabetes and with a high degree of ascertainment. Incidence time series were also found for subjects aged 15–34 (Diabetes Incidence Study in Sweden, DISS, since 1983), with up to 7,369 subjects and with a lower degree of ascertainment compared to SCDR. Regarding age from 40 years and above fewer studies were found, and with a much lower number of subjects with type 1 diabetes. Diabetes incidence in children has had a relative increase of approximately 2% per year since 1938. Incidence rates in children 0–14 years of age show no gender differences, but in subjects aged 15–39 years a male preponderance up to twofold is found. Figures for subjects 40 years or older are more uncertain, but show a fairly equal incidence among men and women. The male preponderance in type 1 diabetes from age 15 up to 40–50 could be due to hormonal influence, with higher peripheral insulin resistance among men in young adults and younger middle age.
Keywords: Gender, Incidence, Prevalence, Sweden, Type 1 Diabetes mellitus.
Current Diabetes Reviews
Title:Time Trends and Gender Differences in Incidence and Prevalence of Type 1 Diabetes in Sweden
Volume: 9 Issue: 4
Author(s): Per E. Wandell and Axel C. Carlsson
Affiliation:
Keywords: Gender, Incidence, Prevalence, Sweden, Type 1 Diabetes mellitus.
Abstract: There are different opinions on a possible sex bias in diabetes. In Sweden we have access to data since the 1930s, making it an ideal model. We aimed to study gender differences and time trends in the incidence and prevalence of type 1 diabetes in Sweden. We found 31 articles on incidence and 8 on prevalence (6 overlapping). Times series on incidence were found regarding children 0–15 years of age (with the Swedish Childhood Diabetes Registry, SCDR, since 1977), with up to 14,721 children with diabetes and with a high degree of ascertainment. Incidence time series were also found for subjects aged 15–34 (Diabetes Incidence Study in Sweden, DISS, since 1983), with up to 7,369 subjects and with a lower degree of ascertainment compared to SCDR. Regarding age from 40 years and above fewer studies were found, and with a much lower number of subjects with type 1 diabetes. Diabetes incidence in children has had a relative increase of approximately 2% per year since 1938. Incidence rates in children 0–14 years of age show no gender differences, but in subjects aged 15–39 years a male preponderance up to twofold is found. Figures for subjects 40 years or older are more uncertain, but show a fairly equal incidence among men and women. The male preponderance in type 1 diabetes from age 15 up to 40–50 could be due to hormonal influence, with higher peripheral insulin resistance among men in young adults and younger middle age.
Export Options
About this article
Cite this article as:
Wandell E. Per and Carlsson C. Axel, Time Trends and Gender Differences in Incidence and Prevalence of Type 1 Diabetes in Sweden, Current Diabetes Reviews 2013; 9 (4) . https://dx.doi.org/10.2174/15733998113099990064
DOI https://dx.doi.org/10.2174/15733998113099990064 |
Print ISSN 1573-3998 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-6417 |
Call for Papers in Thematic Issues
Advancing Diabetic Wound Healing: Mechanisms and Interventions
In recent years, diabetic wounds have become a global health concern with an increase in the incidence of diabetes. Diabetic wounds are a kind of chronic and refractory ulcer. It is generally due to microcirculatory disturbances and reduced levels of endogenous growth factors. Delayed cutaneous wound healing is a chronic ...read more
Advancing Insights into Type 1 Diabetes: From Mechanisms to Management
Type 1 diabetes (T1D) represents a significant global health challenge, requiring a deep understanding of its complex pathophysiology and the development of innovative strategies for prevention, treatment, and management. This thematic issue highlights the latest progress in understanding the autoimmune processes underlying T1D, advances in beta-cell biology, and novel therapeutic ...read more
Oxidative and Inflammatory Responses in the Development of Secondary Diabetic Complications
Diabetes, along with its associated secondary complications, represents a significant global health challenge, contributing significantly to morbidity and mortality. Unhealthy lifestyle habits, reduced physical activity, environmental pollutants, and stress are pivotal factors in the onset of diabetes, particularly type-2 diabetes. Poorly managed hyperglycemia can lead to various complications, including neuropathy, ...read more

- Author Guidelines
- Bentham Author Support Services (BASS)
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
- Announcements
Related Articles
-
Infection and Malignancy Risk in Patients Treated with TNF Inhibitors for Immune-Mediated Inflammatory Diseases
Current Drug Safety Immunomodulation of the Allergic Inflammatory Response: New Developments
Inflammation & Allergy - Drug Targets (Discontinued) 20th National Congress and Conference Abstracts
Endocrine, Metabolic & Immune Disorders - Drug Targets Microbes, Immunity and Multiple Sclerosis: An Update
Current Immunology Reviews (Discontinued) Sepsis: Links between Pathogen Sensing and Organ Damage
Current Pharmaceutical Design Sexual Dimorphism in Autoimmune Disease
Current Molecular Medicine Current Opinion on 3-[2-[(2-Tert-Butyl-Phenylaminooxalyl)-Amino]-Propionylamino]- 4-Oxo-5-(2,3,5,6-Tetrafluoro-Phenoxy)-Pentanoic Acid, an Investigational Drug Targeting Caspases and Caspase-Like Proteases: The Clinical Trials in Sight and Recent Anti-Inflammatory Advances
Recent Patents on Inflammation & Allergy Drug Discovery The Gut Mucosa as a Site for Induction of Regulatory T-Cells
Current Pharmaceutical Design Benefits of GLP-1 Mimetics on Epicardial Adiposity
Current Medicinal Chemistry Inhibitory Smad7: Emerging Roles in Health and Disease
Current Molecular Pharmacology Genetic and Molecular Approaches to the Immunopathogenesis of Multiple Sclerosis: An Update
Current Molecular Medicine Enteric Ecosystem Disruption in Autism Spectrum Disorder: Can the Microbiota and Macrobiota be Restored?
Current Pharmaceutical Design Valproic Acid As Anti-Cancer Drug
Current Pharmaceutical Design Impact of Immune Response on the Use of iPSCs in Disease Modeling
Current Stem Cell Research & Therapy Uveitis in Rheumatic Diseases
Current Rheumatology Reviews From Multiple PAR1 Receptor/Protein Interactions to their Multiple Therapeutic Implications
Current Topics in Medicinal Chemistry Mesenchymal Stem Cells: A Good Candidate for Restenosis Therapy?
Current Vascular Pharmacology Inhibition of Histone Deacetylases: A Pharmacological Approach to the Treatment of Non-Cancer Disorders
Current Topics in Medicinal Chemistry Epigenetics and Periodontal Disease: Hope to Tame the Untameable
Current Gene Therapy Vascular and Cellular Calcium in Normal and Hypertensive Pregnancy
Current Clinical Pharmacology