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CNS & Neurological Disorders - Drug Targets


ISSN (Print): 1871-5273
ISSN (Online): 1996-3181

Vascular Contribution to Alzheimer Disease: Predictors of Rapid Progression

Author(s): Marina Diomedi and Giulia Misaggi

Volume 12, Issue 4, 2013

Page: [532 - 537] Pages: 6

DOI: 10.2174/1871527311312040015

Price: $65


Different courses of Alzheimer disease are observed in clinical practice. The rapidly progressive form could be associated with the presence of a major microcirculatory involvement and hemodynamic insufficiency. This short review aims to provide an overview of the current knowledge of cerebrovascular contribution to Alzheimer disease presentation and progression, hypothesizing the possible vascular markers of rapidly progressive form.

Keywords: Alzheimer disease, cerebral blood flow, disease progression, hemodynamics, risk factors, transcranial Doppler.

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