Generic placeholder image

Current Organic Synthesis


ISSN (Print): 1570-1794
ISSN (Online): 1875-6271

Application of Chiral Bisamide Ligands in Asymmetric Catalytic Syntheses

Author(s): Chan Zhou and Jiaxi Xu

Volume 10, Issue 3, 2013

Page: [394 - 410] Pages: 17

DOI: 10.2174/1570179411310030005

Price: $65


A variety of chiral bisamide ligands have been prepared and widely used in asymmetric catalytic syntheses with highly regioand enantioselective products, especially in the transition-metal-catalyzed asymmetric allylic alkylation reactions. The achievements in the asymmetric allylic alkylation reactions with various nucleophiles have been reviewed. The applications of some typical chiral bisamides in decarboxylative asymmetric allylic alkylation of enol carbonates, [3+2] cycloaddition of vinyl cyclopropanes and alkylidene azlactones, and aldol reactions are also introduced.

Keywords: Bisamide, ligand, asymmetric catalysis, allylic alkylation, nucleophile.

Rights & Permissions Print Cite
© 2024 Bentham Science Publishers | Privacy Policy