Abstract
A variety of chiral bisamide ligands have been prepared and widely used in asymmetric catalytic syntheses with highly regioand enantioselective products, especially in the transition-metal-catalyzed asymmetric allylic alkylation reactions. The achievements in the asymmetric allylic alkylation reactions with various nucleophiles have been reviewed. The applications of some typical chiral bisamides in decarboxylative asymmetric allylic alkylation of enol carbonates, [3+2] cycloaddition of vinyl cyclopropanes and alkylidene azlactones, and aldol reactions are also introduced.
Keywords: Bisamide, ligand, asymmetric catalysis, allylic alkylation, nucleophile.
Call for Papers in Thematic Issues
Biorthogonal Chemistry: A translational Chemical Tool for In Vivo Applications
After the discovery in 1990, bioorthogonal chemistry encompassed a set of diverse, fast-paced selective chemical reactions, facilitating the study of biomolecules under physiological aura without intervening in the biochemical processes. Over the past two decades, significant progress has been witnessed in bioorthogonal reactions such as Staudinger ligation, metal-catalyzed coupling reactions, ...read more
Design and Synthesis of Green Pesticides
The development of new green pesticides is currently one of the hotspots in the field of pesticide research, aiming to develop efficient, environmentally friendly, and safe pesticide products to meet the needs of modern agricultural production. New green pesticides prioritize environmental friendliness and ecological safety. Therefore, during the research and ...read more
Exploring the Role of Chemical Graph Theory in Advancing Current Organic Synthesis
Organic synthesis is a fundamental discipline in chemistry, which is crucial for the creation of complex molecules with diverse applications in pharmaceuticals, materials science, and beyond. However, the process of designing efficient synthetic routes for target molecules remains challenging. Chemical graph theory, a branch of theoretical chemistry, offers powerful tools ...read more
Novel Green Approaches in the Synthesis of Bioactive Molecules
This special issue regards several aspects of green chemistry, focusing on innovative strategies to run organic synthesis reactions in a more environmentally friendly. Interesting articles or reviews about the critical role of green methodologies in reducing the environmental impact of chemical processes are welcome. Moreover, novel methodological studies using sustainable ...read more
Related Books
2-Deoxy-D-Glucose: Chemistry and Biology
Chiral Ionic Liquids: Applications in Chemistry and Technology
Basics of Organic Chemistry: A Textbook for Undergraduate Students
Advances in Organic Synthesis
The Synthetic Methods, Structures, and Properties of the Ca-C σ Bond Organocalcium Containing Compounds
Advances in Organic Synthesis
Chemistry of Bipyrazoles: Synthesis and Applications
Advances in Organic Synthesis
Advanced Nanocatalysis for Organic Synthesis and Electroanalysis
Advances in Organic Synthesis
16
