Abstract
Helicobacter pylori infection has been indicated as the main pathogenic factor in the development of chronic gastritis, peptic ulcer disease, and gastric malignancies. Although the vast majority of infected subjects do not carry but a mild, asymptomatic gastritis, still there are some cases in which the eradication of the infection appears mandatory. This review addresses current anti-Helicobacter regimens and pharmacological resources, and highlights the pros and cons of each of them, according to the most recent and reliable clinical trials. Also, basic recommendations are given, regarding treatment choice in the event of the failure of a first or second line eradicating strategy, and about the implementation of standard regimens with newer antibacterial devices as probiotics.
Keywords: H. pylori Infection, pathogenic factor, anti-Helicobacter regimens, asymptomatic gastritis
Current Medicinal Chemistry
Title: Treatment of H. pylori Infection: A Review
Volume: 12 Issue: 4
Author(s): Marcello Candelli, Enrico C. Nista, Emilia Carloni, Giulia Pignataro, Maria Assonta Zocco, Alossia Cazzato, Cristiana Di Campli, Lucia Fini, Giovanni Gasbarrini and Antonio Gasbarrini
Affiliation:
Keywords: H. pylori Infection, pathogenic factor, anti-Helicobacter regimens, asymptomatic gastritis
Abstract: Helicobacter pylori infection has been indicated as the main pathogenic factor in the development of chronic gastritis, peptic ulcer disease, and gastric malignancies. Although the vast majority of infected subjects do not carry but a mild, asymptomatic gastritis, still there are some cases in which the eradication of the infection appears mandatory. This review addresses current anti-Helicobacter regimens and pharmacological resources, and highlights the pros and cons of each of them, according to the most recent and reliable clinical trials. Also, basic recommendations are given, regarding treatment choice in the event of the failure of a first or second line eradicating strategy, and about the implementation of standard regimens with newer antibacterial devices as probiotics.
Export Options
About this article
Cite this article as:
Candelli Marcello, Nista C. Enrico, Carloni Emilia, Pignataro Giulia, Zocco Assonta Maria, Cazzato Alossia, Campli Di Cristiana, Fini Lucia, Gasbarrini Giovanni and Gasbarrini Antonio, Treatment of H. pylori Infection: A Review, Current Medicinal Chemistry 2005; 12 (4) . https://dx.doi.org/10.2174/0929867053363027
DOI https://dx.doi.org/10.2174/0929867053363027 |
Print ISSN 0929-8673 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-533X |
Call for Papers in Thematic Issues
Advances in Medicinal Chemistry: From Cancer to Chronic Diseases.
The broad spectrum of the issue will provide a comprehensive overview of emerging trends, novel therapeutic interventions, and translational insights that impact modern medicine. The primary focus will be diseases of global concern, including cancer, chronic pain, metabolic disorders, and autoimmune conditions, providing a broad overview of the advancements in ...read more
Cellular and Molecular Mechanisms of Non-Infectious Inflammatory Diseases: Focus on Clinical Implications
The Special Issue covers the results of the studies on cellular and molecular mechanisms of non-infectious inflammatory diseases, in particular, autoimmune rheumatic diseases, atherosclerotic cardiovascular disease and other age-related disorders such as type II diabetes, cancer, neurodegenerative disorders, etc. Review and research articles as well as methodology papers that summarize ...read more
Chalcogen-modified nucleic acid analogues
Chalcogen-modified nucleosides, nucleotides and oligonucleotides have been of great interest to scientific research for many years. The replacement of oxygen in the nucleobase, sugar or phosphate backbone by chalcogen atoms (sulfur, selenium, tellurium) gives these biomolecules unique properties resulting from their altered physical and chemical properties. The continuing interest in ...read more
Current advances in inherited cardiomyopathy
Describe in detail all novel advances in multimodality imaging related to inherited cardiomyopathy diagnosis and prognosis. Shed light to deeper phenotypic characterization. Acknowledge recent advances in genetics, genomics and precision medicineread more
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
- Announcements
Related Articles
-
Current and Future Prospective of a Versatile Moiety: Imidazole
Current Drug Targets The Role of Niacin in Lipid-lowering Treatment: Are we Aiming Too High?
Current Pharmaceutical Design Impact of COX-2 Inhibitors in Common Clinical Practice a Gastroenterologists Perspective
Current Topics in Medicinal Chemistry Adenosine Dysfunction in Epilepsy and Associated Comorbidities
Current Drug Targets Pharmacotherapy in Systemic Lupus Erythematosus
Current Rheumatology Reviews Determination of Interchangeability of Different Brands of Diclofenac Sodium Sustained Release Tablets in Healthy Subjects Using Pharmacokinetic End Points
Letters in Drug Design & Discovery Anti-HSV-1 Activity of Glycyrrhizic Acid Nanoparticles Prepared by Supercritical Antisolvent Process
Current Nanoscience Chest Pain in Children
Current Pediatric Reviews Aspirin as a Chemoprevention Agent for Colorectal Cancer
Current Drug Metabolism Helicobacter Pylori, Zinc and Iron in Oxidative Stress-Induced Injury of Gastric Mucosa
Mini-Reviews in Medicinal Chemistry Meloxicam Prevents Load-Induced Cardiac Hypertrophy in Mice
Immunology, Endocrine & Metabolic Agents in Medicinal Chemistry (Discontinued) Monocyclic and Fused Azines and Azoles as Histamine H<sub>4</sub> Receptor Ligands
Current Medicinal Chemistry Type 1 11 β-hydroxysteroid Dehydrogenase as Universal Drug Target in Metabolic Diseases?
Endocrine, Metabolic & Immune Disorders - Drug Targets Eicosanoids in Prevention and Management of Diseases
Current Molecular Medicine Therapeutic Agents for COVID-19: an Overview
Current Drug Therapy Is Helicobacter pylori Always a "Bad Guy"?
Current Pharmaceutical Design Viscosupplementation with Intra-Articular Hyaluronic Acid for Treatment of Osteoarthritis in the Elderly
Current Pharmaceutical Design Alternative Methods in Eradicating Helicobacter Pylori Infection
Current Pharmaceutical Analysis Job Stress and Blood Pressure: A Critical Appraisal of Reported Studies
Current Hypertension Reviews Cyclooxygenase-2 Inhibitors: A Painful Lesson
Cardiovascular & Hematological Disorders-Drug Targets