Sonochemical Hot-spot Assisted One-pot Synthesis of 4-arylmethylidene - 2-phenyl-4H-oxazol-5-ones Using Nano-MgO as an Efficient Catalyst

Title:Sonochemical Hot-spot Assisted One-pot Synthesis of 4-arylmethylidene - 2-phenyl-4H-oxazol-5-ones Using Nano-MgO as an Efficient Catalyst

Volume: 10 Issue: 4

Author(s): Sadeq Hamood Saleh Azzam, G. T. Chandrappa and Mohamed Afzal Pasha

Affiliation:

Keywords: 4-Arylmethylidene-2-phenyl-4H-oxazol-5-ones, Nano-MgO, hippuric acid, aromatic aldehydes, acetic anhydride, Ultrasonic-irradiation.

Abstract: Twelve 4-arylmethylidene-2-phenyl-4H-oxazol-5-ones were prepared in excellent yield by sonicating a mixture of an araldehyde, hippuric acid and acetic anhydride in the presence of a green heterogeneous NanoMgO as a basic catalyst. The catalytic activity of NanoMgO was found to be higher compared with bulk MgO powder under the same conditions. This method provides several advantages such as short reaction time, high yields, cleaner reaction condition, involves simple and easy workup procedure makes this protocol economically viable.

Cite this article as:

Hamood Saleh Azzam Sadeq, Chandrappa G. T. and Afzal Pasha Mohamed, Sonochemical Hot-spot Assisted One-pot Synthesis of 4-arylmethylidene - 2-phenyl-4H-oxazol-5-ones Using Nano-MgO as an Efficient Catalyst, Letters in Organic Chemistry 2013; 10(4) . https://dx.doi.org/10.2174/1570178611310040010