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Current Medicinal Chemistry


ISSN (Print): 0929-8673
ISSN (Online): 1875-533X

Targeting Multiplicity: The Key Factor for Anti-Cancer Nanoparticles

Author(s): M. Gary-Bobo, O. Vaillant, M. Maynadier, I. Basile, A. Gallud, K. El Cheikh, E. Bouffard, A. Morere, X. Rebillard, P. Puche, P. Nirde and M. Garcia

Volume 20, Issue 15, 2013

Page: [1946 - 1955] Pages: 10

DOI: 10.2174/0929867311320150002

Price: $65


In this mini-review, we focus on different strategies to bring nanotools specifically to cancer cells. We discuss about a better targeting of tumor, combining the characteristics of tumor environment, the increase in nanoparticles life time, the biomarkers overexpressed on cancer cells and different physical methods for non invasive therapies. Here we detail the necessity of a synergy between passive and active targeting for an actual specificity of cancer cells.

Keywords: Cancer, multiple targeting, nanoparticles, non-invasive therapies

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