Generic placeholder image

Current Molecular Medicine


ISSN (Print): 1566-5240
ISSN (Online): 1875-5666

Development of Aptamer-Based Nanomaterials for Biological Analysis

Author(s): Y. Pu, H. Liu, B. Liu, J. Liao, J. Liu, Z. Zhao and W. Tan

Volume 13, Issue 4, 2013

Page: [681 - 689] Pages: 9

DOI: 10.2174/1566524011313040016

Price: $65


Aptamers selected from a large random sequence pool are oligonucleic acid or peptide molecules that bind to a specific target molecule with high affinity and sensitivity. Targets range from small molecules to proteins and peptides, even tissue or cells. As such, aptamers have captured the attention of scientists actively developing technologies for diverse biomedical applications. Particularly, when functionalized with nanomaterials, aptamers offer properties for both biomedical and bioanalytical applications. In this review, these features and properties are discussed with particular emphasis on the use of aptamer-based biosensor/detection platforms.

Keywords: Aptamer, biological analysis, cancer cells, nanomaterials, SELEX

« Previous

Rights & Permissions Print Export Cite as
© 2023 Bentham Science Publishers | Privacy Policy