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Current Pharmaceutical Design

Editor-in-Chief

ISSN (Print): 1381-6128
ISSN (Online): 1873-4286

A Review of Therapeutic Effects of Curcumin

Author(s): Ali Noorafshan and Soheil Ashkani-Esfahani

Volume 19 , Issue 11 , 2013

Page: [2032 - 2046] Pages: 15

DOI: 10.2174/1381612811319110006

Abstract

There is a growing interest in herbal medicine. Scientific studies have demonstrated the beneficial pharmacological effects of curcumin. Curcumin is a bright yellow spice, derived from the rhizome of Curcuma longa Linn. It has been proven that curcumin is a highly pleiotropic molecule which can be a modulator of intracellular signaling pathways that control cell growth, inflammation, and apoptosis. Curcumin might be a potential candidate for the prevention and/or treatment of some diseases due to its anti-oxidant, antiinflammatory activities and an excellent safety profile. We present an updated concise review of currently available animal and clinical studies demonstrating the therapeutic effect of curcumin.

Keywords: Curcumin, therapeutic effects, review, herbal medicine, rhizome, intracellular signaling pathways, cell growth, inflammation, apoptosis, anti-oxidant


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