Survey of Recent Literature Related to the Biologically Active 4(3H)-Quinazolinones Containing Fused Heterocycles

Title:Survey of Recent Literature Related to the Biologically Active 4(3H)-Quinazolinones Containing Fused Heterocycles

Volume: 20 Issue: 6

Author(s): Martine Demeunynck and Isabelle Baussanne

Affiliation:

Keywords: Quinazoline, quinazolinone, nitrogen heterocycles, antitumor agents, antiviral

Abstract: the present review focuses on the synthesis and biological evaluation of polycyclic 4(3H)-quinazolinones containing fused aromatic or heteroaromatic rings. The first part of the review is related to compounds with ring fused to the pyrimidine part of the quinazoline core. Most of the quinazolinone alkaloids belong to this class of molecules. The second part presents molecules bearing extra ring(s) fused to the benzo moiety of the quinazolinone skeleton. Their structural diversity opens new fields in the search of active molecules.

Cite this article as:

Demeunynck Martine and Baussanne Isabelle, Survey of Recent Literature Related to the Biologically Active 4(3H)-Quinazolinones Containing Fused Heterocycles, Current Medicinal Chemistry 2013; 20(6) . https://dx.doi.org/10.2174/0929867311320060006