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Mini-Reviews in Medicinal Chemistry


ISSN (Print): 1389-5575
ISSN (Online): 1875-5607

Benzimidazole Derivatives as Potential Anticancer Agents

Author(s): Ahmed A. El Rashedy and Hassan Y. Aboul-Enein

Volume 13, Issue 3, 2013

Page: [399 - 407] Pages: 9

DOI: 10.2174/1389557511313030008

Price: $65


Benzimidazole ring system is found in many bioactive heterocyclic compounds because of their diverse biological and clinical applications. Furthermore, benzimidazole derivatives are structural isosters of naturally occurring nucleotides, thus they can interact with biological macromolecules such as proteins, enzymes and receptors. This review discusses the benzimidazole derivatives which possess anticancer activity of medicinal efficacy.

Keywords: Substituted Benzimidazoles, anticancer activity

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