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Current Organic Synthesis


ISSN (Print): 1570-1794
ISSN (Online): 1875-6271

Palladium-Catalyzed Cycloaddition of 1,3-Butadiynes with Water: An Alternative Efficient Catalytic System for Atom-Economic Synthesis of 2,5-Disubstituted Furans

Author(s): Qingwei Zheng, Ruimao Hua and Tao Yin

Volume 10 , Issue 1 , 2013

Page: [161 - 164] Pages: 4

DOI: 10.2174/1570179411310010007

Price: $65


An efficient Pd(PPh3)4/2,5-norbornadiene-catalyzed cycloaddition of 1,4-disubstituted 1,3-butadiynes with H2O under basic conditions for straightforward and simple synthesis of 2,5-disubstituted furans is described.

Keywords: Cycloaddition, 1, 3-butadiynes, furan derivative, palladium, water

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