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Current Analytical Chemistry

Editor-in-Chief

ISSN (Print): 1573-4110
ISSN (Online): 1875-6727

Electrochemical Oxidation of Flavonoids at a Nano- Metal Oxide Modified Carbon Paste Electrodes and Determination Their Levels in Human Urine

Author(s): Lai-Hao Wang, Hsiu-Hua Liu

Volume 9, Issue 1, 2013

Page: [143 - 149] Pages: 7

DOI: 10.2174/1573411011309010143

Price: $65

Abstract

We constructed nano-metal oxide (tin oxide, cerium oxide, cobalt oxide, iron oxide, nickel oxide, gold oxide, and silver oxide) -modified carbon paste electrodes (CPEs) for detecting flavonols (kaempferol, myricetin, and quercetin) and flavones (luteolin and apigenin) using high-performance liquid chromatography with an electrochemical detector (HPLC-ECD). Flavonoids are more efficiently catalytically oxidized on a gold oxid e-modified CPE than on a bare CPE. For direct current mode, with the current at a constant potential, and measurements with suitable experimental parameters, a linear concentration from 40 to 1600 ng mL-1 was found. The limits of quantification for flavonoids were below 0.5 ng. The developed method detected flavonoids in urine samples. Findings using HPLC-ECD and HPLC with an ultraviolet detector were comparable.

Keywords: Nano- metal oxide, Modified carbon paste electrodes, Flow-through voltammetric detector, Flavonoids, Human urine


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