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Combinatorial Chemistry & High Throughput Screening


ISSN (Print): 1386-2073
ISSN (Online): 1875-5402

One-Pot, Three-Component Synthesis of Spirooxindoles Catalyzed by ZnO Nano-Rods in Solvent-Free Conditions

Author(s): Mona Hosseini-Sarvari and Mina Tavakolian

Volume 15, Issue 10, 2012

Page: [826 - 834] Pages: 9

DOI: 10.2174/138620712803901144

Price: $65


Recyclable ZnO nano-rods catalyst as a most efficient and straightforward protocol for one-pot, threecomponent synthesis of spirooxindole derivatives at room temperature under solvent-free conditions in both reaction media and work-up procedure is described. This method is of great value because of its environmentally benign character, easy handling, high yields, convenient operation (grinding), room temperature, low cost and green.

Keywords: Multi-component reactions, nano rod ZnO, solvent-free, spirooxindoles.

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